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J Goudemand

Publications and source records attributed to J Goudemand.

114 records · Page 7Linked to original sources
PubMedDate not supplied

["Spontaneous" hematoma of the psoas in Gaucher's disease].

The authors report a case of iliac muscle haematoma responsible for inguinal pain in a patient with Gaucher's disease type I. This exceptional cause of pain must now be considered side by side with the classical femoral head osteonecrosis and infectious coxitis. Magnetic resonance imaging appears to be the most sensitive and most specific examination for the aetiological diagnosis of hip pain in Gaucher's disease. In the absence of thrombocytopenia and franck abnormality of coagulation, the spontaneousness of the haematoma is discussed.

Adult↗
PubMedDate not supplied

[Acute agranulocytosis induced by pyramidon or phenothiazines. Apropos of 31 cases].

The authors present 31 cases of acute agranulocytosis due to drugs. 27 resulted from amidopyrine poisoning and 4 were due to phenothiazines. The clinical picture in most cases, was that of severe septicemia with lesions of the mucosae. On blood count agranulocytosis was complete, associated on bone marrow examination with an appearance of selective hypoplasia of the granular series or an aspect of maturation blockage at the stage of the myelocyte or the metamyelocyte. The course was fatal in 6 cases. A search for leukocyte agglutinating antibodies, carried out in 29 cases, was positive in only 5 cases. These facts correspond, on the whole, to the, clinical and etiological data found in the literature. Although the agranulocytoses induced by phenothiazines, seem to be mainly of toxic origin, the agranulocytoses induced by amidopyrine associated both an immunological mechanism and a toxic mechanism. Among all the biological tests proposed, the most useful is the le ukocyte agglutination test, but the serological diagnosis is rarely conclusive.

Acute Disease↗
PubMedDate not supplied

[Investigation of circulating immune complexes in some diseases associated with platelets hyperdestruction process (author's transl)].

A possible relationship between the presence of circulating immune complexes (CIC) and the platelet-bound IgG levels was investigated in 38 patients with some diseases associated with a no drug-related platelets hyperdestruction process of which 33 had idiopathic thrombopenic purpura (ITP). By using the 125I-C1q binding test, these CIC were only detected in 4 of the 42 tested sera. No correlation was noticed between the percentage of C1q binding and the platelet IgG levels evaluated by the quantitative hemolysis inhibition test. These results do not allow to consider the involvement of CIC in the thrombocytopenia genesis observed in these diseases.

Adolescent↗
PubMedDate not supplied

[Heredity and childhood psychoses : histocompatibility antigens (HLA A and B) and early onset childhood psychoses (author's transl)].

We first consider current arguments in favor of a genetic etiology of childhood psychoses. These psychoses have to be separated in early psychoses (before age 5) and late onset ones (between 5 years and adolescence). These late onset psychoses appear to be genetically determined and related to schizophrenia, while early psychoses may be in part genetically related and subject to environmental factors. We also report a study on HLA in early onset psychoses in the North of France, which could not show any association between HLA system and the psychoses.

Adolescent↗