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Biomedical subjects

J Godard

Publications and source records attributed to J Godard.

At least 73 records · Page 4Linked to original sources

[Primary cerebral lymphoma. Diagnostic and therapeutic values. Apropos of 4 cases].

The authors report four recent cases, of primary cerebral Lymphoma discovered since the use of the C.T. scan. Even though rare, the incidence of this tumor seems to be in slowly increase. The lesions on the C.T. scan are too variables and the surgical biopsy is necessary for the diagnosis. The primary cerebral Lymphoma should be considered more and more like the others Lymphomas. For this reason, they have started the treatment after surgical biopsy, with chemotherapy followed by radiotherapy associated with corticotherapy. The two last patients, are still alive with a follow up of 36 months for one of them. The prognosis seems to us, better as much as the diagnosis and the treatment was started early.

Adult↗

Cranioplasty with acrylic methyl methacrylate resin. Modified procedure--technical note.

A modified methylmethacrylate cranioplasty is presented. After preparation of the skull defect, a Teflon net is placed and fitted over it, overlapping the border by one centimeter. The plastic material is spread over the Teflon net in the skull defect and is removed as soon as it becomes firm. Next, the plate is perforated at several points and then is fixed with Vicryl stiches between the Teflon net and the epicranium. This procedure is simple and fast. The fixation is firm; the result is good.

Bone Cements↗

Lipoma in the cerebellopontine angle.

A case of lipoma in the cerebellopontine angle is reported. Intracranial lipomas are very rare, especially in the cerebellopontine angle. To our knowledge, only four cases, including our own, have been operated upon. Until now, total extirpation has not been possible. The singular appearance on computed tomography scanning of this dysembryoplasia is presented together with a bibliography of this subject.

Adult↗

[Obstetrical consequences of female circumcision. Study in 71 circumcised African women].

The delivery of 71 African women who had been circumcised was studied against a control of 781 women who were not circumcised. We have not been able to find any difference as far as caesarean section, forceps delivery or fetal distress in the two groups that were studied. The only difference is a higher frequency of perineal injury in the group of circumcised women.

Circumcision, Male↗

[Ellis-van Creveld syndrome. Contribution of echography to prenatal diagnosis. Apropos of a case].

The Ellis Van Creveld syndrome gives rise to a dwarf showing chondroectodermal dysplasia. We report a case where the diagnosis was made antenatally by ultrasound. It showed that the length of the femur was shorter than the mean for the gestational age and it also showed six fingers. A review of the literature demonstrates that it is possible to make the diagnosis of skeletal dysplasia prenatally using ultrasound.

Adult↗

[Monotherapy of Pseudomonas aeruginosa septicemia with azlocillin].

Azlocillin was administered alone to seven patients without malignant or blood disease presenting with septicaemia caused by Pseudomonas aeruginosa. In 6 cases the infection developed after surgery and in 3 of these it was responsible for a state of shock, twice associated with acute anuric renal failure. The minimum inhibitory concentrations of azlocillin varied from 2 to 32 micrograms/ml; 5 strains were resistant to carbenicillin. The minimum inhibitory to minimum bactericidal concentrations ratio, measured on five occasions, was equal to 2. Bacterial eradication was obtained in 6 patients. One patient with multivisceral failure died during treatment and in this case the responsible organism had become resistant to azlocillin.

Adult↗

[Nerve regeneration through a venous graft in the rat. Preliminary results].

An experimental study of nerve regeneration in rats was realized after sectioning 8 mm of the sciatic nerve and interpositioning a vein-graft to replace the portion of nerve which has been removed. The vein-graft was taken at the neck level, far away from the point of suture between vein and nerve, a procedure which seems to prevent the problems of scabbing. A histological and electrophysiological analysis was carried out on 16 grafts, over periods ranging from 4 weeks to 4 months. The nerve and venous dissections were realized under a stereoscopic microscope. A certain degree of amyotrophy appeared in the external-posterior region of the thigh, directly related to the muscular dissection and the partial paralysis caused by the section of the common peroneal nerve. The electrophysiological recordings in vivo provide proof of nerve regeneration but reveal the absence of any correlation between the time of recovery and the time of induction. Examination under the light microscope confirms the regeneration of the nerve inside of the vein-graft, with an augmentation of myelin sheaths, which increase with time both in number and in thickness. The vein-wall acts as a guide but the passage of a few nervous filaments outside of the graft itself is observed. Examination under the electron microscope furnishes important information on myelin sheaths. The results are of excellent quality, but to better appreciate and evaluate them, we envisage a further study, this time to be carried out on another animal species.

Animals↗