Search PubMed⌕ Search

Biomedical subjects

J Gnarpe

Publications and source records attributed to J Gnarpe.

46 records · Page 3Linked to original sources
PubMed1994

Chlamydia pneumoniae (TWAR): a common agent in acute bronchitis.

Patients seeking medical attention for respiratory infections were investigated with serology and culture for Chlamydia pneumoniae to investigate the prevalence of C. pneumoniae in a specific geographical area and its association with respiratory disease. Evidence for C. pneumoniae infection was found in approximately 25% of cases. 71% of patients with C. pneumoniae had symptoms from the lower respiratory tract as compared to 29% of the others. We conclude that C. pneumoniae can be a major cause of acute bronchitis.

Acute Disease↗
PubMed1993

An unusual manifestation of Chlamydia pneumoniae infection: meningitis, hepatitis, iritis and atypical erythema nodosum.

A 37-year-old man was admitted to hospital with fever, muscle tenderness, headache and mild exanthema on the right thigh. During his hospital stay, the headache worsened and aseptic meningitis was diagnosed. A bilateral iritis developed, and the exanthema developed into an atypical erythema nodosum. In liver function tests, pathological results were recorded. Vasculitis was suspected but could not be confirmed. All serological tests proved negative except for a fourfold titre rise to Chlamydia pneumoniae. We concluded that the meningitis, hepatitis, iritis and atypical erythema nodosum were most probably due to a C. pneumoniae infection.

Adult↗
PubMed1993

Chlamydia pneumoniae in Swedish patients.

Chlamydia pneumoniae infections have earlier been described as mycoplasma-like illnesses in young people, and also appear to be associated with community-acquired pneumonia in adults. In this retrospective study, 12.2% (23/188) of patients with pneumonia who required hospitalization during the 3 years 1985-87 had serological evidence of recent C. pneumoniae infection. Many of these patients had symptoms similar to ornithosis. The most interesting finding was that half of the patients with a 4-fold IgG antibody titre rise to C. pneumoniae also had an increased alkaline phosphatase concentration.

Alkaline Phosphatase↗
PubMed1992

Prevalence of Mycoplasma pneumoniae in subjectively healthy individuals.

Subjectively healthy persons were investigated for the presence of Mycoplasma pneumoniae in throat cultures. During a peak period of M. pneumoniae incidence, 13.5% of 758 healthy volunteers were found to harbour the bacterium in the throat. The investigation was continued, and during a subsequent period of 11 months, the incidence of M. pneumoniae isolated decreased to 4.6% of 499 volunteers. All new blood donor sera 1990-1991 (422 sera) were screened for the presence of antibodies to M. pneumoniae; it was found that there was a fluctuating but significant number of individuals with positive serology based on a single test occasion.

Adolescent↗
PubMed1991

Diagnosis and prevalence of persistent chlamydia infection in infertile women: tissue culture, direct antigen detection, and serology.

Specimens for chlamydial culture, direct fluorescent antibody (DFA) test, two enzyme immunoassays (EIA) for antigen detection, and serum for chlamydial antibodies were collected from 256 infertile women. Specimens were taken from the tubes during tuboplasty and from the cervix and endometrium during laparoscopy or tuboplasty. Antibodies to Chlamydia trachomatis were found four times more often in patients with signs of prior pelvic inflammatory disease (PID) than in infertile women with normal pelvic findings. Only 48 (37%) of 131 patients with signs of prior PID had a history of PID. Ten or more C. trachomatis elementary bodies (EBs) per smear were found in 21 (8.2%) of 256 patients. Six patients had a positive culture or a positive antigen EIA test. All six had high numbers of EBs in the DFA test. We conclude that routine culture and EIA antigen tests detect only a minority of persistent chlamydia infections in this population, but subjective factors in the interpretation of DFA methods must be considered.

Adult↗