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Biomedical subjects

J Glover

Publications and source records attributed to J Glover.

At least 91 records · Page 5Linked to original sources

Seeding arterial prostheses with vascular endothelium. The nature of the lining.

Arterial prostheses seeded with autogenous vascular endothelium demonstrate a well-organized, cellular, inner lining. To determine the nature of the lining cells, six animals underwent replacement of the infrarenal aorta with Dacron prostheses. During the preparation of three such grafts, endothelium was scraped from the saphenous vein with a steel wool pledget, suspended in chilled Sack's solution, and mixed with blood used to preclot the graft. This suspension was omitted from the three control grafts. After six weeks, the grafts were removed, rinsed and examined. Fluorescent Factor VIII related antigen (F VIII-RA) strongly stained the lining cells. Silver nitrate Haütchen and electron microscopy preparations revealed a lining pattern characteristic of vascular endothelium. Endothelial cell-specific Weibel-Palade bodies were identified in the lining cell cytoplasm. Masson's trichrome staining revealed a relatively collagen-poor connective tissue within the seeded fabric. Transmission electron microscopy disclosed vascular smooth muscle cells between the seeded graft fabric and the lining cells. Vasa vasorum, arising from the outer capsule, penetrated the fabric to supply the inner capsules of the seeded grafts. It is concluded that the cells lining seeded canine arterial prostheses are true vascular endothelium supported by vascular smooth muscle cells, that the lining contains minimal connective tissue, and that vasa vasorum develop. Unseeded control grafts lacked these features.

Animals↗

Circannual changes in plasma concentrations of immunoreactive retinol-binding protein and luteinizing hormone in male and female Japanese quail.

In a single experiment, lasting for 18 months, male and female quail were exposed to an annual cycle of artificial photoperiod synchronized with sunrise and sunset, and their plasma levels of immunoreactive retinol-binding protein (IRBP) and LH were monitored at frequent intervals. Plasma levels of both IRBP and LH showed a repeating annual cycle with maximal levels during the spring/summer, the period of reproductive activity and highest rate of egg-laying, and minimal levels during the autumn/winter. Plasma levels of IRBP and LH were significantly, but only weakly, correlated with each other. The possible role of LH in the regulation of plasma IRBP during reproduction is discussed. Evidence is presented that the proportion of IRBP which does not carry retinol (retinol-binding apoprotein; apoRBP) varies throughout the female breeding cycle and that the high apoRBP concentration noted in the spring/summer period may be related to the deposition of retinol in the egg.

Animals↗

Xerophthalmia.

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Child↗

Seasonal changes in the plasma retinol-binding holoprotein concentration of sheep.

1. Seasonal variations in plasma retinol-binding holoprotein concentration have been found in two groups of entire ewes and in a control group of wethers (castrated rams). 2. In each group retinol-binding holoprotein level was minimal in summer and increased to peak values in September just before the autumn breeding season.

Animals↗

Procedures to increase some aspects of creativity.

Instructions reinforcement (team points), and practice were applied to four behaviorally defined creative behaviors of eight fourth- and fifth-grade students. All four aspects (number of different responses, fluency; number of verb forms, flexibility; number of words per response, elaboration; and statistical infrequency of response forms, originality) were demonstrated to be under experimental control. The procedures also raised students' scores on Torrance's tests of creativity. Application of the experimental procedures may well be practical for classroom teachers.

Child↗

Ureteroneocystostomy versus ureteropyelostomy: a comparison in the same renal allograft series.

Of the 132 transplants in our series 44 patients underwent reconstruction by ureteropyelostomy (group 1) and 88 underwent reconstruction by ureteroneocystostomy (group 2). The rates of major urologic complications were 11 percent in group 1 and 4 per cent in group 2. These results support the widely held opinion that ureteroneocystostomy is the superior method for urinary reconstruction in renal allograft cases. However, the alternative of ureteropyelostomy should be part of every transplant surgeons' armamentarium, especially for cadaver transplants when ureteral blood supply may be compromised.

Cadaver↗

Melanin as a predictor in the acquisition of developmental skills.

Seventy-two subjects were randomly drawn across grades K-12 and administered an instrument designed to measure developmental skills within seven skill area categories. A three-way ANOVA, fixed effects model, was used for data analysis. Subjects were blocked by eye color, sex, and grade level for the purpose of investigating the relationship between eye color and sex to self-paced and reactive behaviors. Significant differences were obtained on the main effect of eye color in five of the seven categories examined. There were three significant first order interactions (sex X eye color) and one three-way interaction. The findings support the hypothesis of Worthy that eye color is a dependable predictor of subjects' general behavioral competency area (self-paced or reactive) and adds considerable support for his thesis that self-paced and reactive behaviors are to some degree inherited.

Age Factors↗