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Biomedical subjects

J Giron

Publications and source records attributed to J Giron.

122 records · Page 7Linked to original sources
PubMed1982

Fluoride deposition in the bones of rats determined by fluoride and X-ray diffraction analysis.

Rats were given drinking water containing up to 300 parts/10(6) F and the conversion of hydroxyapatite to fluoridated apatite was estimated chemically and by X-ray diffraction. The differences of the mean fluoride uptakes from the very different concentrations of fluoride given were significant. Prolonged washing of the bones with demineralized water released 5-10 per cent from the fluoride uptake. Formation of fluoridated apatite was evident by decreases in the a parameter of the hydroxyapatite phase. In the washed bones, there was no appreciable transformations in the a parameters. The co-existence of Mg-containing beta-Ca3(PO4)2 with the apatite phase was detected in heated bone samples. The amount of beta-Ca3(PO4)2, its dependence on the age of the bones and its Mg content are interdependent.

Animals↗
PubMed1982

Opportunistic infection in previously healthy women. Initial manifestations of a community-acquired cellular immunodeficiency.

Opportunistic infections and unusual tumors have been reported in an unprecedented outbreak of community-acquired cellular immune deficiency among homosexual and drug-abusing men. We report five women with the same syndrome. The women were residents of metropolitan New York City closely associated with drug abuse either by personal use (our patients) or close sexual contact with an abuser (one patient). One patient was bisexual. All five patients developed Pneumocystis carinii pneumonia as well as combinations of other opportunistic infections including oral candida, disseminated mycobacteria, and ulcerative herpes simplex infections. All patients had marked depression of cellular immune function. Three patients died. The appearance of this syndrome in women has important implications with regard to the epidemiology and etiology of this emerging syndrome.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Bronchial aneurysms mimicking aortic aneurysms: endovascular treatment in two patients.

Bronchial artery dilatation and aneurysm formation is a potential complication of local inflammation, especially in bronchiectasis. When the bronchial artery has an ectopic origin from the inferior segment of the aortic arch, aneurysms may mimick aortic aneurysms. Despite this particular location, endovascular treatment is possible. We report two such aneurysms that were successfully embolized with steel coils.

Aneurysm↗
PubMedDate not supplied

[Postpneumonectomy thoracic empyema and dosimetric CT scan. Report of two cases and review of the literature].

Following a pneumonectomy for cancer, the patients are classically observed by clinical examination and standard chest X-ray. However, torpid empyemas can be missed when they occur after the period of hospitalization and when they are not accompanied by a fever. At the time of postoperative radiotherapy, the dosimetric CT scan constitutes the first examination providing objective information of the endothoracic content. It is therefore necessary on this occasion to assure the normality of the postpneumonectomy pleural space while checking that the substituted liquid is homogeneous and above all that the internal mediastinal part of the cavity has a concave appearance. If that is not the case, an empyema should be suspected. The diagnosis, confirmed by a cytobacteriological examination of the pleural fluid, constitutes a counterindication of the radiotherapy. We present two cases of postpneumonectomy paucisymptomatic empyema which were diagnosed during the course of postoperative radiotherapy when the initial dosimetric CT scan was pathologic and could have allowed an earlier diagnosis.

Diagnosis, Differential↗
PubMedDate not supplied

Mediastinal and hilar lymphadenopathy due to Pneumocystis carinii infection in AIDS patients: CT features.

OBJECTIVE: Extrapulmonary involvement by Pneumocystis carinii (PC) in acquired immunodeficiency syndrome (AIDS) patients is uncommon. Our purpose is to describe three AIDS patients with low cluster differentiation cell (CD4) counts, who were receiving aerosol pentamidine prophylaxis, and who had large noncalcified hilar and mediastinal lymphadenopathy. MATERIALS AND METHODS: Chest radiography, CT, and clinical and laboratory records of three AIDS patients who had radiographic evidence of mediastinal and hilar lymphadenopathy were retrospectively reviewed. RESULTS: Symptoms were quite similar in all patients: weight loss, fever, cough, and mild dyspnea. Mediastinal and hilar widening was noticed on chest radiography. Contrast-enhanced chest CT revealed multiple noncalcified lymphadenopathy with supracarinal predominance in all cases. Mediastinoscopy with mediastinal and hilar lymph nodes sampling was performed in all patients. Histologic examination of the biopsy specimens demonstrated a necrotic foamy tissue without any calcification, and silver stain coloration showed abundant PC organisms in each case. CONCLUSION: In AIDS patients, PC infection should be considered as a possible cause of noncalcified hilar and mediastinal lymphadenopathy along with such possibilities as atypical infections and neoplasms, especially in severely immunocompromised hosts (low CD4) with aerosol pentamidine prophylaxis.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

High resolution chest CT in tuberculosis: evolutive patterns and signs of activity.

PURPOSE: The purpose of our study was to determine evolutive patterns and signs of active tuberculosis on high resolution CT (HRCT) scans. METHOD: We followed up over 15 months 27 patients with postprimary pulmonary tuberculosis that was proven bacteriologically. CT scans were performed before, during, and after 6 months of anti-tuberculosis treatment. Both 10-mm-thick sections and 1.5-mm-thick HRCT scans were performed. RESULTS: Ground-glass pattern was noticed 26 times, 9 times after 2 month treatment and only 2 times after 6 month treatment. Among these two patients, one did not undergo his treatment properly and the other one had an additional bacterial infection. Centrilobular nodules (n = 17) and poorly marginated nodules (n = 21) were present only before treatment. Reticular pattern (intralobular and septal thickening), interstitial nodules, and fibrosis were seen both before and after treatment. Ground-glass pattern, poorly marginated nodules, and infiltrates as well as centrilobular nodules were related to an active infection. CONCLUSION: This HRCT may be helpful to demonstrate activity in patients suspected of having tuberculosis and to assess antituberculous treatment efficiency.

Adolescent↗
PubMedDate not supplied

Pre-therapeutic evaluation of laryngeal carcinomas using computed tomography and magnetic resonance imaging.

A prospective and comparative computed tomography (CT)/magnetic resonance imaging (MRI) study on 90 patients with endoscopically examined and histologically proven laryngeal malignancy is presented. Post-operative pathological and intra-radiological (CT vs. MRI) correlations are established. We conclude that MRI is the method of choice for staging laryngeal malignancies.

Carcinoma, Papillary↗
PubMedDate not supplied

[Vagal paraganglioma associated with a rare malformation of the aortic arch. Apropos of a case and review of the literature].

The authors report about a very peculiar case of cervical paraganglioma which had two specific features. This is a familial case with 2 sisters presenting with bilateral paragangliomas. In addition, this patient's aortic trunk is very peculiar, with a retroesophageal right subclavian artery and, above all, a divided intrathoracic right common carotid artery, producing an ascending pharyngeal supply for the right paraganglioma, which can be embolized without any risks of reflux.

Adult↗
PubMedDate not supplied

[Pulmonary hemangiopericytoma. Apropos of a case and review of the literature].

Hemangiopericytoma is a rare vascular tumor of pericyte origin and of variable but always preoccupying potential since falling within the category of sarcomas. A thoracic localization is rare and primary pulmonary parenchyma lesions even more so, only 87 cases being reported in the literature. Radiological diagnostic criteria are of weak specificity, diagnosis being provided by thin section CT scan imaging with contrast. The differential diagnosis of these vascular tumors includes arteriovenous fistula, pulmonary varices, other vascular tumors or even organized bronchomucoceles. The value of CT scan puncture is obviously limited. The course is unpredictable since even histopathology findings fail to provide definitive data.

Adult↗
PubMedDate not supplied

[MRI/CT x-ray comparison in the pre-operative evaluation of cancer of the larynx. Apropos of 46 cases].

The authors present the comparative value of CT scan and MRI in the pre-operative staging of 46 laryngeal carcinomas. The "in depth" evaluation conducts the choice of conservative surgery. CT scan is the reference but MRI reveals itself as effective and even more in certain cases. The spontaneous contrast gradient for soft tissues of the MR imaging explains this effectiveness of the method. The paraglottic space and the subglottic extension are more easily studied by MRI. If the expansion of the MRI Unities allows this indication of the pre-operative staging of laryngeal carcinomas is an excellent one.

Humans↗