Biomedical subjects
J Giron
Publications and source records attributed to J Giron.
[Pleural plaques and thoracic imaging].
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[Magnetic resonance imaging of pulmonary coin lesion and bronchopulmonary cancer].
Magnetic resonance imagery (MRI) is less sensitive than computed tomography (CT) for the detection of pulmonary masses and cannot detect calcifications within such masses. MRI performed during the work-up for bronchial cancers has often been compared with CT scans: neither T nor N can be evaluated with more precision. Nevertheless, there are certain specific indications such as the exploration of proximal tumours with suspected extension into the mediastinum including cardiac and vascular invasion, tumours of the aorto-pulmonary window, the Pancoast-tobias syndromes, and tumours situated near the thoracic wall or the spine.
[Interventional radiology of the thorax].
The authors review the various thoracic interventional radiology techniques currently used by a medicoradiosurgical team. CT-guided needle biopsy has an important place in the diagnostic approach to parenchymal as well as mediastinal and pleuroparietal tumours. CT also allows drainage of various thoracic collections. Embolizations of bronchial arterial haemoptyses, pulmonary arteriovenous aneurysms or post-catheterisation false aneurysms are effective therapeutic procedures. Percutaneous extraction of foreign bodies generally avoids the need for open surgery. Superior vena cava and tracheobronchial stents are palliative treatments allowing a better quality of survival in patients with superior vena cava compression. CT-guided sympatholysis and in situ fibrinolysis have certain specific indications in pulmonary embolism.
Mast cells' contribution to the fibrosing alveolitis of the scleroderma lung.
Fibrosing alveolitis is frequently seen in scleroderma. Although usually causing progressive symptomatology, it may be found in patients reporting no respiratory symptoms. Mast cells may play a role in the pathogenesis of skin fibrosis in scleroderma. We determined the mast cells and other cellular content, as well as measuring the inflammatory mediators in the bronchoalveolar lavage fluid (BALF) in 17 scleroderma patients and nine control subjects to correlate BALF features with fibrosing alveolitis as determined by lung function testing and high-resolution computed tomographic scans. Bronchoalveolar lavage cells were enumerated after May-Giemsa-Grünwald (MGG), alcian blue, and safranine blue staining. Histamine, tryptase, eosinophil cationic protein, hyaluronic acid, and neutrophil-specific myeloperoxidase were measured by radioimmunoassay. In comparison with normal subjects the BALF of scleroderma patients showed an increased percentage of mast cells (p < 0.002, Mann-Whitney U test), and increased levels of histamine (p < 0.005), tryptase (p < 0.02), and hyaluronic acid (p < 0.004). The BALF of the eight scleroderma patients with an abnormal chest X-ray had a significantly greater number of mast cells (p < 0.04, Mann-Whitney U test), and significantly higher levels of histamine (p < 0.03, Mann-Whitney U test) and tryptase (p = 0.02, Mann-Whitney U test) than the nine scleroderma patients with a normal chest X-ray. This study demonstrates the importance of mast cells and mast-cell activation in the pathogenesis of the fibrosing alveolitis of scleroderma.
[Magnetic resonance imaging in pleural and chest wall diseases].
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[Recurrent opacity in a patient with long-standing tuberculosis].
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CT and MR evaluation of laryngeal carcinomas.
A prospective and comparative tomography (CT)/magnetic resonance imaging (MRI) study on 110 patients with endoscopically examined and histologically proven laryngeal malignancy is presented. Post-operative pathological and intraradiological (CT vs. MRI) correlation are established. We conclude that MRI is the method of choice for staging laryngeal malignancies. MRI can also be used for follow-up (recurrence after surgery, evolution under radiation therapy).
[Magnetic resonance imaging in pneumology].
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[Contribution of magnetic resonance imaging to the exploration of the mediastinum].
Magnetic resonance imaging (MRI) already has a number of indications in exploration of the mediastinum, the most frequent of which being exploration of vascular pathologies facilitated by visualization of vascular lumina without need for a contrast medium, MRI can provide detailed information concerning the size, relations and wall thickness of these vessels ans sometimes of aneurysmal thrombosis. It also makes it possible to study aortic dissections and venous diseases of the mediastinum. As regards mediastinal masses, MRI complements computerized tomography (CT): it is better than the latter to distinguish vascular relations and it provides aetiological arguments based on the intensity of T1 and T2-weighted signals.
[Magnetic resonance imaging of the respiratory airways and the pulmonary parenchyma].
In the study of the proximal airways, MRI is mainly appropriate for the trachea and the mainstem bronchi, in case of tracheal stenosis or tumors. CT remains the reference examination for the distal airways. In alveolar condensation, MRI may help differentiating some of the involved materials (blood, lipids). Lastly, the role of MRI is limited in interstitial pathology, even though some indications may be appearing: fibrosis following radiation therapy, determination of the inflammatory component.
[A rare peritoneal tumor: malignant mesothelioma].
A peritoneal mesothelioma is described. The diagnosis was established by histological study. The clinical and radiological presentation are nonspecific. Contact with asbestos fibers is rarely reported and not obtained in this case. The clinical, radiological, histological presentations and therapeutic aspects are discussed.
[An uncommon thoracic tumor: an hour-glass shaped parietal lipoma. Contribution of MRI and CT].
One case of transmural thoracic lipoma is reported. Thoracic lipomas are rare tumors. This report illustrates the usefulness of CT and MRI in the preoperative diagnosis and subsequent evaluation of transmural thoracic lipoma.
Chest radiography and high resolution computed tomography of the lungs in asthma.
CT scans have been studied only in asthmatics who were smokers, and no such study has been performed in patients with chronic uncomplicated asthma where a permanent bronchial destruction is likely to occur after a long course of the disease. The object of the study was to characterize CT-scan abnormalities and determine whether bronchial destructive lesions may be observed. Fifty-seven adults with chronic asthma of variable severity and etiology and 10 normal subjects were studied. None of the subjects smoked. Chest radiographs and HR-CT scans were performed in all patients. To discriminate between reversible and irreversible CT-scan abnormalities, two examinations were made in 10 patients with acute asthma both before and 2 wk after parenteral high dose corticosteroid treatment. The chest radiographs showed the expected abnormalities of asthma in 37.8% of the asthmatics. CT scans were abnormal in 71.9% of the asthmatics. Reversible abnormalities included mucoid impactions, acinar pattern, and lobar collapse. Irreversible abnormalities included bronchiectasis, bronchial wall-thickening, sequellar line shadows, and emphysema. Most of these abnormalities are likely to be related to bronchial destruction.
[Cervico-mediastinal cystic lymphangioma].
Anterior cervico-mediastinal tumors in children, especially if they are cystic, often correspond to the diagnosis of cystic hemolymphangioma. CT and Chest US are contributive for the diagnosis and the pre-operative staging.
[Wegener's disease: value of thoracic computed tomography. Apropos of a case and review of the literature].
The authors demonstrate the value of thoracic HR-CT in a case of Wegener's granulomatosis with a typical presentation. This uncommon disease, often has a pseudo-infectious or pseudo-neoplastic appearance and the diagnosis can be difficult as indicated by a review of the literature.
[Primary mediastinal myxoid liposarcoma. Apropos of a case].
Liposarcoma is an uncommon mediastinal tumor provides limited CT histologic date. The prognosis depends on the histological grade and surgical possibilities. The authors report a case of mediastinal liposarcoma and discuss the correlation between imaging findings, outcome and histological status.
[Blind ureter associated with a dysplastic kidney and ureterocele. Apropos of a case and review of the literature].
The association of a blind ureter with dysplastic kidney and ureterocele is known in children but are in adults. This paper presents one case, and provides simple diagnostic clues which help to recognize the malformation.