Search PubMed⌕ Search

Biomedical subjects

J Ghisolfi

Publications and source records attributed to J Ghisolfi.

100 records · Page 6Linked to original sources
PubMedDate not supplied

[Evaluation of the lean body and/or muscle mass in children receiving artificial nutrition. Comparative value of anthropometric data and the urinary excretion of creatinine and 3-methylhistidine].

Lean body mass was estimated in 15 adequately nourished and afebrile children, aged 1 to 24 months, receiving parenteral and/or enteral nutrition with anthropometric measurements (30 analyses). At the same time, muscle mass was evaluated from the 24 hour-urinary excretion of creatinine and 3-methylhistidine. Statistical computations showed and excellent correlation between the results obtained by both methods. The stable conditions for these children receiving artificial nutrition (normal nitrogen, carbohydrate and fat intakes, excluding exogenous creatinine and 3-methylhistidine) allow the use of these two biological measurements as markers of muscle mass and provide a control for the validity of the results of anthropometric measurements. Urinary excretion of 3-methyl-histidine not correlated with that of creatinine or with anthropometric data should suggest an increase in myofibrillary catabolism. These 3 simple, non invasive tests may be particularly useful in patients receiving artificial nutrition, to study the short- and long-term efficacy of the methods of artificial feeding used and to modulate the intake of nitrogen, carbohydrates and fat.

Anthropometry↗
PubMedDate not supplied

[Chronic diarrhea in nonspecific colopathies in children. Trial of etiological classification].

305 children with non specific colopathies were studied with respect to the etiologic factors which may be responsible for the onset of the diarrheic syndrome. Epidemiologic factors (ethnic group, mode of housing, standard of living, parents's age and profession) did not appear to play a significant role and studies of familial and personal histories did not appear to be of any help. On the contrary, analysis of the diet showed a high incidence of nutritional imbalances (75.2% of cases) especially with respect to hyperprotidic diets. The role of a major and repeated antibiotic therapy and of psychologic problems may be suggested in 46 (15%) and 36 (11.8%) of the 305 cases, respectively. Fiberoptic and histologic investigations of the proctosigmoid mucosa were performed in 67 children: an inflammatory aspect was found in 22. In 21 of these 22 cases, no etiologic factors could be found and these cases, especially those occurring before 6 months of age, might belong to a special clinical entity.

Adolescent↗