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Biomedical subjects

J Gawler

Publications and source records attributed to J Gawler.

29 records · Page 2Linked to original sources

Intracranial epithelial cysts. Report of two cases.

The authors report two cases with large unilocular intracerebral epithelial cysts. Diagnosis was facilitated in both patients by computerized tomography (EMI scanner). The clinical and diagnostic aspects of previously reported cases are reviewed, and the etiology and pathogenesis of these cysts discussed.

Adult↗

A comparison of computer asisted tomography (EMI scanner) with conventional neuroradiologic methods in the investigation of patients clinically suspected of intracranial tumor.

Computerized tomography has been used as the initial radiologic investigation among 212 intracranial tumor suspects. Ninety-five of these patients were ultimately shown to have tumors as a result of all their investigations. Eighty tumors were clearly defined by EMI scanning, four further scans were suspicious but not unequivocally abnormal and six scans showed complications of the tumor rather than the lesion itself. Thus, only five scans were falsely negative in the presence of a tumor. The false positive and false negative rates for EMI scanning have been compared with conventional techniques and computerized tomography shown to compare favourably with angiography or encephalography.

Brain Neoplasms↗

Computerized axial tomography: the normal EMI scan.

Computerized axial tomography using the EMI scanner as a new method of using x-rays in diagnosis. The technique displays intracranial and orbital structures in the transverse plane. The appearances of normal EMI Scans are described and correlated with cerebral and orbital anatomy seen in transverse section.

Brain↗

Idiopathic Parkinsonism treated with an extracerebral decarboxylase inhibitor in combination with levodopa.

The clinical actions of levodopa in Parkinsonism, given with and without an extracerebral decarboxylase in hibitor, L-alpha-methyldopahydrazine, were compared. Twenty-one patients were investigated in a "double-blind cross-over" study, administering levodopa in maximum tolerated dosage. L-Alpha-methyldopahydrazine failed to augment the overall therapeutic actions of levodopa but it consistently alleviated nausea. It is concluded that L-alpha-methyldopahydrazine will prove useful in the management of some Parkinsonian patients who have difficulty in taking levodopa alone.

Adult↗