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Biomedical subjects

J Gaudin

Publications and source records attributed to J Gaudin.

12 recordsLinked to original sources

[Acquired non hypertrophic pyloric stenosis in children].

UNLABELLED: Pediatric non hypertrophic pyloric stenosis (NHPS) are uncommon. Their causes and treatments are debated. MATERIAL AND METHOD: Retrospective review of all cases of NHPS from 3 pediatric surgery services during the period 1984-2002. RESULTS: Six children, aged 17 months to 15 years, underwent surgery for NHPS. Clinical symptoms, food vomiting and loss of weight, were present for several weeks before the diagnosis of NHPS was made. The diagnosis was peptic stenosis in 3 cases and has not been established in 3 cases. Search for Helicobacter pylori was negative in all cases. Failure of specific medical treatment and endoscopic dilatations led to pyloric resection in 3 cases and pyloroplasty in 3 cases. Post operative course was uneventful with normal oral feeding and normalisation of weight status. Histologic data were aspecific. No recurrence was observed. DISCUSSION: We discuss the origin of the pyloric stenosis, regarding clinical, operative and pathological data: were the stenosis the cause or consequence of peptic ulcer? Peptic disease is always advocated, but difficult to prove and may be excessively incriminated. Late symptomatic congenital and acquired idiopathic pyloric stenosis should be recalled. In all cases of proved pyloric stenosis, after failure of medical and endoscopic treatment, a simple surgical procedure (pyloroplasty) associated with medical treatment seems to be effective. CONCLUSION: The diagnosis of NHPS should be suspected in a child with food vomiting and loss of weight if his age is not concordant with hypertrophic pyloric stenosis. Upper gastro-intestinal series and endoscopy are diagnostic. The precise cause of the stenosis is more difficult to asses. When the medical treatment fails, a pyloroplasty is usually curative.

Adolescent↗

The venous hilum of the testis and epididymis: anatomic aspect.

The venous return from the testis is effected by 3 venous pathways: the pampiniform plexus gathrs the centripetal and centrifugal paths of the testis with the marginal vein of the epididymis; the deferential vein accompanies the ductus deferens; and the cremasteric vein travels more superficially between the internal and external spermatic fasciae on its way to the inferior epigastric vein. At the caudal pole of the testicle these different pathways form such close connections as to constitute a real vascular junction.

Adult↗

[Results of the treatment of acute intestinal invaginations by radiopaque enemas. Apropos of 70 cases].

Since May 1982, when the pediatric surgery group of Rouen has published their study in the 39th congress of "Societe Française de Chirurgie Infantile", regular surgical attitude in treatment of intussusception was abandoned by our team. Seventy cases were admitted in our section in the period (06-82/06-86), age ranged from one month to nine years. All except one were subjected to radio-opaque enema as a method of treatment with success rate of 89% reduction. Optimum conditions, failures (7 case), perforation (one case) and recurrence are presented. We conclude the efficacy of this treatment in condition of a rigorous technic.

Barium Sulfate↗

Serum iron determination using ferene triazine.

The synthesis and characterisation of a new colorimetric reagent for iron, 3-(2-pyridyl)-5,6-bis(2-furyl)-1,2,4-triazine are described. Peak assignments and chemical shifts of the high resolution 13C nmr spectrum are given. The reagent forms a tris iron(II) complex with epsilon max of 32000 Lcm-1 mol-1 at 577 nm. The results of precision, linearity and recovery studies for use of the reagent in direct serum iron determinations are reported. Thiourea effectively suppresses copper interference for the serum iron determinations. With the procedure used, the presence of hemolysed cells in the serum had no effect on serum iron levels recorded.

Chromogenic Compounds↗

Spontaneous spinal epidural hematoma in a 22-month-old girl.

The authors report the case of a 22-month-old girl who developed cervical pain, neck stiffness, and quadriparesis over 12 days. An epidural hematoma was removed, with complete recovery after 6 months. There was no history of trauma. A search of the literature revealed eight previous cases of spontaneous spinal epidural hematomas in children under the age of 10 years.

Female↗

Copper interference in the determination of iron in serum using ferrozine.

Random samples of sera were analysed for copper and iron. Based on the data presented in this paper and substantiated by other workers, the ferrozine method for the determination of serum iron is the most sensitive method currently available, provided the interference due to copper is effectively eliminated.

Colorimetry↗