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Biomedical subjects

J G Sullivan

Publications and source records attributed to J G Sullivan.

31 records · Page 2Linked to original sources

Adaptive hypertrophy of the digit following little finger to thumb transposition.

This is a long-term retrospective study of eight patients who had undergone little finger to thumb transposition after traumatic thumb loss in order to evaluate the presence of long-term changes in the transposed digit. The transposed little finger, contralateral (nontransposed) little finger, and contralateral thumb were compared using standardized measurements of size, comparison photographs, x-rays, and volume determination using silicone mold impressions of these digits. Significant and marked hypertrophy of the transposed digit was demonstrated in all these patients. Comparison radiographs demonstrated that this enlargement was due to hypertrophy of both soft-tissue and osseous components. This study demonstrates that the little finger transposed to the thumb position undergoes an adaptive hypertrophy to become more thumblike in appearance as well as function.

Adaptation, Physiological↗

Aggressive malignant hemangiopericytoma in the neck.

Hemangiopericytomas are rare vascular tumors, one fourth of which occur in the head and neck. These lesions are characteristically slow growing and slow to metastasize. We describe an otherwise healthy patient with a hemangiopericytoma on the left side of his neck that metastasized to his chest wall within 3 months after the tumor was first observed. The metastasis occurred while the patient was receiving radiation therapy. The patient died soon afterward. This case illustrates the aggressive malignant potential of hemangiopericytomas.

Head and Neck Neoplasms↗

Bacteriologic status of necrotic tissue in necrotizing pancreatitis.

To confirm the accuracy of guided percutaneous aspiration (GPA) in distinguishing sterile from infected pancreatic necrosis, we have performed Brown-Brenn tissue Gram stains on pancreatic and peripancreatic necrotic tissue removed operatively in 15 patients. In eight patients judged to have sterile necrosis on the basis of negative cultures of pancreatic exudate obtained first preoperatively (by GPA) and then intraoperatively, necrotic tissue debrided at surgery was also free of bacteria. In seven patients judged to have infected necrosis on the basis of positive cultures of pancreatic exudate obtained first preoperatively (by GPA) and then intraoperatively, necrotic tissue debrided at surgery harbored a considerable number of bacteria. We conclude that GPA targeted to areas of necrosis accurately distinguishes infected necrosis from sterile necrosis, and in infected necrosis, the solid necrotic tissue as well as the fluid component contains bacteria. We therefore believe that infected necrosis is not likely to be eradicated by catheter drainage and should be treated by surgical debridement.

Bacteriological Techniques↗

Central cavitary necrosis: differentiation from pancreatic pseudocyst on CT scan.

Central cavitary necrosis of the pancreas has a computed tomography CT appearance of a well-defined sausage-shaped mass with a low-density center and convex margins, usually conforming to the pancreatic contour. Several other entities, including pancreatic pseudocyst, may have a similar appearance. Since the treatment of central cavitary necrosis differs considerably from that of these other entities, it is important to differentiate them. We present CT criteria that help distinguish central cavitary necrosis from pancreatic pseudocyst and from a variety of other intrapancreatic and peripancreatic masses.

Diagnosis, Differential↗