Search PubMed⌕ Search

Biomedical subjects

J G Spangler

Publications and source records attributed to J G Spangler.

At least 19 recordsLinked to original sources
PubMed1998

Body fat, fat distribution, and psychosocial factors among patients with Type 2 diabetes mellitus.

Diabetes, a risk factor for cardiovascular disease, requires lifestyle modifications (diet, exercise, weight loss). The relations between body mass index, waist-hip ratio (WHR), and psychosocial indicators, such as affect and stress, among 302 diabetic patients from a clinic and a neighborhood health center were analyzed. Data included stress and mood scale responses, body size (height, weight, and WHR) and potential confounders (physical activity, energy intake, and diabetes duration). In univariate analyses, body mass index was positively associated with stress and inversely associated with positive affect only in women. Multiple regression analyses indicated that stress was associated with body mass index and negative mood was associated with the WHR. The findings suggested that stress and affect may be important correlates of body fat among women with Type 2 diabetes, leading to more complications. Healthcare providers can help women with Type 2 diabetes lose weight and lower the risk of cardiovascular disease by recognizing and helping them deal with these psychosocial issues.

Adult↗
PubMed1998

Church-related correlates of tobacco use among Lumbee Indians in North Carolina.

BACKGROUND: Although minority populations suffer a disproportionately higher burden of tobacco-attributable morbidity and mortality, the church appears to be a promising avenue through which to pursue tobacco-cessation interventions in these communities. This report describes church-related correlates of tobacco use among the Lumbee Indians in North Carolina, a population with a high prevalence of tobacco use, strong ties to tobacco-related agriculture, and high levels of church participation. METHODS: A cross-sectional telephone survey of 400 adult Lumbee Indians was carried out in Pembroke, a town in Robeson County, NC. The questionnaire elicited information on tobacco use, demographic and social support information, knowledge and practices related to tobacco agriculture and traditional Native American tobacco use and church participation. RESULTS: Sixty-three percent of participants were church members and 82% said the church is "very important" to the Lumbee community. In bivariate analysis, church attendance over the past year correlated with age, education, gender, number of close friends and relatives, marital status and current smoking status. Church attendance was not related to current smokeless tobacco use or participation in tobacco-related agriculture. Current smokers who had not attended church in the past year smoked significantly more cigarettes per day than current smokers attending church more often. In logistic regression, participants attending church weekly or more often were 73% less likely to be current smokers (adjusted odds ratio [AOR] = 0.27, 95% confidence interval [CI] = 0.11-0.68). Among ever-smokers, participants having attended church infrequently in the past year were 79% less likely to have quit (AOR = 0.21, 95% CI = 0.07-0.65). Having participated in tobacco agriculture as a child predicted current Christian views on tobacco use. DISCUSSION: Tobacco use, common among Lumbee adults, correlates with a variety of demographic and social support variables. In addition, these data are the first to uncover a dose-response relationship between church attendance and number of cigarettes smoked per day by current smokers, and the relationship between childhood participation in tobacco agriculture and Christian views on tobacco use. Our results should be useful in designing a church-based tobacco-cessation intervention among Lumbee Indians.

Adult↗
PubMed1997

Prevalence and predictors of tobacco use among Lumbee Indian women in Robeson County, North Carolina.

Tobacco use among some Native American tribes is high compared to the overall US population. Little is known, however, about tobacco use among Native Americans in North Carolina, a state with strong economic ties to tobacco. To assess the epidemiology of tobacco use in this population, data from the North Carolina Native American Cervical Cancer Project was reviewed. Nine hundred eighty-two Lumbee Indian women in Robeson County provided general demographic information as well as information on cancer risk knowledge, attitudes and behaviors during the 5-year study. Women were selected from the community using a random sample of 5200 persons from the tribal roll of approximately 40,000 persons. 20.6% of women were current smokeless tobacco users, while 23.7% were current smokers. Demographic and social support predictors were unique for the different types of tobacco use. Cigarette smoking was associated with younger age, higher education, excellent or good self-reported health, having a recent physical exam, separated or divorced marital status, low church participation, and alcohol consumption. Conversely, use of smokeless tobacco was associated with older age, lower education level, fair or poor self-reported health, widowed marital status, and having a high number of friends. These data show a high prevalence of smokeless tobacco use among women in this population, and a contrast in the predictors of tobacco use by source. Intervention programs for tobacco use cessation should be sensitive to these differences.

Adult↗
PubMed1997

Correlates of tobacco use among Native American women in western North Carolina.

OBJECTIVES: This study examined correlates of tobacco use among Cherokee women. METHODS: Prevalence rates were analyzed for 614 randomly selected Eastern Band Cherokee women. RESULTS: The prevalence rates for current smokeless tobacco use and smoking were 8% and 39%, respectively. Smokeless tobacco use correlates included lower education and having consulted an Indian healer. Smoking correlates included younger age, alcohol use, no yearly physical exam, separated or divorced marital status, and lack of friends or church participation. CONCLUSIONS: Smoking rates among these women were slightly above national rates. The association of smokeless tobacco use with having consulted an Indian healer may help in understanding Cherokee women's smokeless tobacco use.

Adolescent↗
PubMed1997

Osteoporosis in women.

Many preventive and treatment strategies are now available for osteoporosis, offering many women the opportunity to forego its many complications. Exercise with calcium and vitamin D supplements is recommended for most patients. Estrogens are a preferred treatment but not acceptable to many women. Alendronate, a bisphosphonate, recently became available to treat osteoporosis. Calcitonin, subcutaneous or intranasal, also can be useful.

Adult↗
PubMed1997

Alcohol, tobacco and illicit drug use among women.

Although the prevalence of alcohol, tobacco, and illicit drug use among women is lower than that among men, women suffer unique adverse health effects from these substances. Furthermore, the use of these substances during pregnancy poses special risks to mother and fetus, including placental accidents, intrauterine growth retardation, congenital anomalies, and premature birth. Primary care clinicians should ask all women about their patterns of alcohol, tobacco, and illicit drug use and should offer targeted interventions to those using these products.

Adolescent↗
PubMed1996

Alendronate: a bisphosphonate for treatment of osteoporosis.

The bisphosphonates have been investigated over the past two decades for the treatment of various diseases of bone and calcium metabolism that are characterized by increased bone resorption, including osteoporosis, Paget's disease, primary hyperparathyroidism, hypercalcemia of malignancy and metastatic bone disease. The bisphosphonate alendronate was recently approved by the U.S. Food and Drug Administration as a therapy for postmenopausal osteoporosis. This agent is currently the bisphosphonate of choice for clinical use. In postmenopausal osteoporosis, alendronate has been shown to increase bone mineral density and to decrease the rate of new fractures. Adverse effects are not usually a problem when 10 mg per day of alendronate is given with at least 6 oz of water 30 minutes before ingestion of the first food or beverage of the day.

Alendronate↗
PubMed1995

Smokeless tobacco: epidemiology, health effects and cessation strategies.

Smokeless tobacco is an extremely addictive substance with a high rate of use in certain demographic groups, such as adolescents and Native Americans. In the past 20 years, the use of smokeless tobacco has almost tripled. Health risks include leukoplakia (a premalignant oral lesion), oral cancer and systemic nicotine effects such as elevated blood pressure and serum cholesterol levels. To avoid or control these effects, family physicians should identify patients who use smokeless tobacco and encourage and support cessation efforts. Patients who are unsure about quitting need the risks of their habit personalized, and those who are actively trying to stop using smokeless tobacco need emotional and, in some cases, therapeutic support (e.g., nicotine replacement therapy). The family physician should encourage patients who appear motivated to stop using smokeless tobacco to set a quit date in the very near future. However, all smokeless tobacco users--regardless of their motivation to quit--need to be followed to ensure compliance with cessation advice or to detect medical complications from use of this form of tobacco.

Algorithms↗
PubMed1995

Screening, health promotion, and prevention in women.

Many health promotion and disease prevention recommendations are specific to adult women. Given their strategic position within families, women often hold the responsibility for the health and well-being of all family members.

Adult↗
PubMed1994

Uses and safety of acyclovir in pregnancy.

Acyclovir, an antiviral nucleoside analogue, is a widely used agent highly specific for herpes simplex and varicella-zoster viruses. Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety. This drug has not been studied prospectively in large numbers of pregnant women and lacks the Food and Drug Administration's approval for gestational use unless benefits clearly outweigh potential fetal harm. However, data published since acyclovir became available do not indicate increased adverse effects related to its use in pregnancy, especially if prescribed in selected situations, such as disseminated primary herpes simplex infections or maternal varicella pneumonia. This article reports the impact of inadvertent acyclovir exposure on a woman during the first trimester of pregnancy and reviews the literature on acyclovir's pharmacology, safety profile, and potential uses during pregnancy.

Acyclovir↗
PubMed1993

The influence of gender and race on mean body temperature in a population of healthy older adults.

Body temperature is known to vary with environmental conditions, physical activity, and illness. There is also some suggestion that body temperature is higher in women than men, and higher in blacks than whites. This study was undertaken to determine if previously described differences in body temperature found in relatively uncontrolled settings associated with gender and race can be reproduced under carefully controlled conditions. Temperature was measured orally with calibrated mercury-in-glass thermometers in 92 healthy community-dwelling volunteers aged 64 years and older. Environmental conditions were carefully controlled and patients with physical conditions or medication regimes known to alter body temperature were excluded. The mean body temperature for all subjects was 36.86 degrees C +/- 0.23 degrees C. The means for white men and women did not differ significantly. There was a statistically significant difference between black and white women, with blacks having 0.13 degrees C higher temperature. We conclude that body temperature varies with race in older women. No significant gender-related difference in normal body temperature was found in these healthy elderly white men and women. Differences in body temperature between men and women found in younger patient populations may reflect the temperature elevations in women associated with menstruation.

Age Factors↗
PubMed1993

Predicting exercise and smoking behaviors in diabetic and hypertensive patients. Age, race, sex, and psychological factors.

OBJECTIVE: To predict exercise and smoking behaviors in primary care patients with chronic diseases (insulin-dependent diabetes mellitus [IDDM], non-insulin-dependent diabetes mellitus [NIDDM], and hypertension) using standardized measures of stress, affect, and family function. DESIGN: Survey by a self-administered health risk appraisal and the Family APGAR Scale (measuring family function), the Brief Encounter Psychosocial Instrument (measuring coping with psychological stress), and the Affect Balance Scale (measuring positive and negative affect). SETTINGS: Large family practice center, university medical center pediatrics clinic, and community health center. PARTICIPANTS: Volunteers meeting World Health Organization criteria for IDDM (n = 83) or NIDDM (n = 322), and volunteers with documented hypertension (n = 140). MAIN OUTCOME MEASURES: Exercise levels at or above 2510 kJ/wk; smoking status; and number of cigarettes consumed per day. RESULTS: Smoking status in all groups was lower than that measured nationally. Stepwise logistic regression showed a correlation between positive affect and higher exercise levels among patients with IDDM and NIDDM, but lower levels among hypertensives. Psychological stress correlated with current smoking among patients with IDDM. In pooled models, whites were much more likely than blacks to exercise at higher levels and to be former or nonsmokers; however, among smokers, whites consumed more cigarettes per day. Among smokers with IDDM, males were much more likely to be moderate to heavy smokers. CONCLUSIONS: Among patients with IDDM, NIDDM, and hypertension, psychosocial stress, affect, age, race, and sex differentially predict exercise and smoking behaviors. The lower-than-national prevalence of smoking in these groups may indicate increased responsiveness to the stop-smoking message. Black diabetic and hypertensive patients, in particular, may require increased health promotion efforts.

Adult↗
PubMed1993

Prevalence and predictors of problem drinking among primary care diabetic patients.

BACKGROUND: Alcohol abuse among patients with diabetes mellitus is dangerous and complicates therapy, but its prevalence and the factors that predict it are unknown. This study examined the prevalence of problem drinking among a large number of primary care diabetic patients, exploring its relation to age, race, sex, psychological factors, and other health behaviors. METHODS: Volunteers with insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus were surveyed at three primary care practice sites. Patients completed a health risk appraisal designed to elicit alcohol use and other health practices, and two psychometric instruments: the Brief Encounter Psychosocial Instrument and the Affect Balance Scale. Fasting blood glucose and hemoglobin A1C levels were also determined. RESULTS: Of 395 diabetic patients, 32 (8.1%) had a drinking problem as defined by answering yes to the question "Have you ever had a drinking problem?" or reporting their last drink to be within 24 hours, or both. Patients with a drinking problem coped less well with psychological stress and had a more highly negative affect than those without a drinking problem. Depression, black race, and male sex were significantly associated with problem drinking (odds ratios = 8.42, 2.70, and 3.80, respectively). Problem drinking did not predict glycemic control but was associated with smoking and less frequent glucose monitoring. CONCLUSIONS: The prevalence of problem drinking among patients with diabetes mellitus appears lower than among other medical outpatient populations and is in keeping with the prevalence found in community surveys. While the lack of association between problem drinking and glycemic control in diabetic patients may be surprising, these data help define the characteristics of this subgroup of diabetic patients and highlight the need for family physicians to intensify alcohol screening efforts in this population.

Adolescent↗
PubMed1989

Vibrio cholerae non-serogroup O1 cystitis.

We report a case of a patient who developed cystitis caused by non-serogroup O1 Vibrio cholerae after swimming in the Chesapeake Bay. Treatment was empirical, with complete symptomatic resolution. Genitourinary tract infections by Vibrio spp. are uncommon but should be considered when cystitis occurs after saltwater exposure in appropriate geographic regions.

Adult↗