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Biomedical subjects

J G Sirois

Publications and source records attributed to J G Sirois.

3 recordsLinked to original sources

Acute myocardial infarction.

Because of advances in reperfusion therapy and improved outcomes through the use of treatment adjuncts, the morbidity and mortality from AMI have been significantly reduced in the past decade. Reperfusion therapy is now the standard of care for all patients who meet eligibility criteria. Equally important in the treatment of AMI, however, are the many treatment adjuncts that are universally available (Table 1). Aspirin and beta-blockers should be used in all patients without contraindications. Heparin, in turn, has a clear role in many but not all patients. Finally, the best application of magnesium has yet to be determined.

Adrenergic beta-Antagonists↗

Prognostic value of the emergency department cardiogram for in-hospital complications of acute myocardial infarction [corrected].

STUDY OBJECTIVE: To identify patients who are admitted from the emergency department with chest discomfort who are at low risk for life-threatening complications. DESIGN: Retrospective chart review. SETTING: A 450-bed military medical center providing active duty and military beneficiaries. TYPE OF PARTICIPANTS: Six hundred twenty-one patients admitted to an ICU from the ED with the chief compliant of chest discomfort. MEASUREMENTS AND MAIN RESULTS: Study participants were placed into low- and high-risk groups based on clinical criteria and ECGs. The groups were compared with respect to occurrence of life-threatening complications during the hospital course. Three of the 262 patients in the low-risk group experienced life-threatening events; two died. Twenty-nine of the 224 high-risk patients experienced life-threatening events; 17 died . Results were statistically evaluated using Fisher's exact test. Significance was achieved at a value of P < .01. CONCLUSION: Patients who meet low-risk group criteria have a low likelihood of immediate life-threatening events and could be admitted to an intermediate care unit.

Arrhythmias, Cardiac↗