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J G Meran

Publications and source records attributed to J G Meran.

62 records · Page 4Linked to original sources
PubMed1990

[New classification criteria of chronic polyarthritis].

The criteria for the classification of the rheumatoid arthritis were defined more precisely, reduced and simplified in 1987 by the American Rheumatism Association. The more detailed specification was achieved at the cost of sensitivity. We find the revision positive as the classification criteria are supposed to mainly serve the purpose of systematic organisation and as a base for multicentered studies. Only then they can give a little help in diagnostic orientation. Never the criteria can take the place of the individual differential diagnosis and the observation of the development of the disease.

Arthritis, Rheumatoid↗
PubMed1990

[Concept and criteria of spondylarthritis].

Since several rheumatic disease share common features, they led to the concept of the spondarthritides: ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritides, juvenile oligoarthritis (type II), and questionable pustolotic arthro-osteitis and Behçet's disease. Furthermore undifferentiated spondarthritides have to be considered. They occur more frequently than ankylosing spondylitis. Definite ankylosing spondylitis is classified according to the New York-criteria, which, however, do not identify the early stage of the disease. In these cases early diagnostic criteria proved to be useful. In a multicenter study the so-called ESSG-criteria were recently introduced for the classification of the whole group of spondarthritides. They are also helpful for the nosological classification of undifferentiated spondarthritides.

Arthritis, Rheumatoid↗
PubMed1990

[Progress in therapy of spondylarthritis].

An update of the wide spectrum of therapeutic measures in the spondarthritides is presented with the example of ankylosing spondylitis. Most important is a life style adjusted to the disease with daily exercises and complementary physiotherapy. The most significant measures of physiotherapy, drug treatment, operation, and radiotherapy are discussed. Preliminary results indicate a long-term effect of sulfasalazine in ankylosing spondylitis. Peculiarities in the treatment of psoriatic arthritis and of entheropathic arthritides are pointed out.

Anti-Inflammatory Agents↗
PubMed1990

[First somatic human gene therapy in the USA approved].

The clinical protocol to treat infants with severe combined immuno deficiency due to adenosine deaminase (ADA) deficiency by means of gene thereapy has been approved recently. The Human Gene Therapy Subcommittee and the Recombinant DNA Advisory Committee (RAC) of the National Institutes of Health (NIH) concluded the review on July 30th and opened the door for the first federally approved somatic Human Gene Therapy.

Adenosine Deaminase↗