Search PubMed⌕ Search

Biomedical subjects

J G Meechan

Publications and source records attributed to J G Meechan.

At least 91 records · Page 5Linked to original sources
PubMed1990

Does beta 2 adrenergic agonism affect local anaesthetic efficacy?

It is theoretically possible that adrenaline might increase local anaesthetic efficacy by a specific beta 2 adrenergic agonistic mechanism by which nerve cell membranes are hyperpolarized. This study compares the anaesthetic efficacy of a local anaesthetic containing the beta 2 adrenergic agonist salbutamol to adrenaline-containing and plain local anaesthetic solutions following intradermal injections. The findings indicate that beta 2 adrenergic agonism did not affect local anaesthetic efficacy in the model employed.

Albuterol↗
PubMed1990

A laboratory investigation of a new design of self-aspirating syringe.

A new design of dental cartridge syringe which incorporates a double self-aspirating mechanism has been investigated under controlled conditions in the laboratory. The new design was compared to two self-aspirating syringes which have been available for some time, namely the Astra and Aspiject syringes. The new syringe aspirated as effectively as the Astra design and was better in this respect than the Aspiject. The method used to examine the syringes involved tests which might be of value in creating standards for dental local anesthetic cartridges.

Anesthesia, Dental↗
PubMed1989

Clinical experience in oral surgery with 2 different automatic aspirating syringes.

The efficacy of 2 designs of automatic aspirating syringe was investigated in 440 patients receiving regional block anaesthesia in the mandible. The incidence of positive aspiration was significantly different between operators and between syringes. Positive aspiration was achieved in 18.9% of patients at some stage during administration of the local anaesthetic solution.

Anesthesia, Dental↗
PubMed1988

The effects of two different dental local anesthetic solutions on plasma potassium levels during third molar surgery.

The influence of two different dental local anesthetic solutions on plasma potassium levels during third molar surgery has been investigated in a single-blind cross-over study in twelve volunteers. The solutions employed were 2% lidocaine (xylocaine) containing 1:80,000 epinephrine and 3% prilocaine (Citanest) containing 0.03 IU/ml felypressin. The different treatments produced similar effects on blood pressure and heart rate. However, the effect on plasma potassium levels differed significantly in the early postinjection period.

Adult↗
PubMed1988

The effect of smoking on immediate post-extraction socket filling with blood and on the incidence of painful socket.

The effect of habitual smoking on post-extraction socket filling with blood and on the incidence of painful socket, was investigated. Data were collected from 2417 adult dental out-patients in whom 3541 extractions were performed under local anaesthesia. Post-operative socket filling with blood was significantly reduced in smokers, compared with non-smokers (p less than 0.01). There was a higher incidence of painful socket in heavy smokers (20 or more cigarettes per day), compared with nonsmokers (p less than 0.05). There was a significant relationship between immediate post-extraction socket blood level and the incidence of painful socket; sockets which showed poorer filling were more likely to develop painful socket (p less than 0.02). Smoking appeared to have an adverse effect upon the healing of extraction wounds.

Adolescent↗
PubMed1987

Local anaesthesia and dry socket. A clinical investigation of single extractions in male patients.

1533 single intra-alveolar permanent tooth extractions in males were investigated in a study to determine if the type and technique of local anaesthesia influenced the occurrence of dry socket. The results show that the incidence of dry socket was significantly greater after the use of Xylocaine compared to Citanest and that the use of repeated injections or intraligamental techniques increased the likelihood of this painful post-extraction condition.

Anesthesia, Dental↗