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Biomedical subjects

J G May

Publications and source records attributed to J G May.

At least 91 records · Page 5Linked to original sources
PubMed1978

Recording monocular VEPs under binocular conditions.

This report describes a technique for recording the visual evoked potential (VEP) arising from 1 eye under conditions of binocular pattern stimulation. The subject views a sinusoidally modulated vectographic checkerboard with orthogonally oriented polarizing filters before the eyes. This technique results in waveforms that contain monocular VEPs distributed in time. The technique is sensitive to interocular suppression and controls for the influence of various extraneous sources of variability. It is useful in clinical VEP testing.

Evoked Potentials↗
PubMed1976

Spatial frequency-contingent color aftereffects.

Two-dimensional Fourier analysis of checkerboards reveals that major components are at a 45 degree angle to the check edges. After adapting to chromatic checkerboards, subjects who viewed achromatic grating stimuli reported that complementary color aftereffects are aligned with spatial frequency components rather than with the edges in the pattern.

Adaptation, Ocular↗
PubMed1976

Behavioral and biochemical effects of neonatal treatment of rats with 6-hydroxydopa.

Rats receiving injection of either 6-hydroxydopa (60 mug/g) or saline on Days 1, 3, and 5 of life were studied in adulthood on a number of behavioral tasks before being sacrificed at 8 or 12 months for NE assay. The treated rats exhibited impaired passive avoidance, less shock-induced aggression, and more locomotor open-field activity than the control rats. There were no differences between the groups in male copulatory behavior, food and water intake, or thermoregulation. In comparison to the saline rats, 6-hydroxydopa rats showed elevated levels of endogenous NE in lower brainstem regions, e.g., midbrain and pons-medulla, as well as cerebellum. Hypothalamic NE level was not affected. Significant depletions of NE were obtained in the hippocampus and neocortex.

Aggression↗
PubMed1969

The presence of a temporal discrimination in the conditioned emotional response with humans.

Six college students participated in matching-to-sample tasks. Conditioned emotional response (CER) training consisted of pairing a tone with a "painful" level of shock. Three of the subjects demonstrated response suppression, one subject showed facilitation, and two showed no change. Analysis of response rate during the tone interval indicated that, for those subjects who showed response suppression, the decrease in response rate was greatest immediately before onset of the unconditioned stimulus. This temporal discrimination was similar to that obtained with infrahumans.

Conditioning, Classical↗