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Biomedical subjects

J G Lapierre

Publications and source records attributed to J G Lapierre.

23 records · Page 2Linked to original sources

Pulmonary function abnormalities in symptom-free children after bronchiolitis.

Twenty-three children less than 18 months old who had clinical and radiological evidence of bronchiolitis and remained symptom-free thereafter were studied to determine pulmonary function ten years later. Abnormal Pao2, Viso V and RV/TLC ratio were found in the majority of subjects, and 31.3% had abnormalities in all three tests; four and one-half percent had exercise-induced bronchospasm. These changes indicate a residual parenchymal or airways lesion following bronchiolitis.

Asthma↗

Vascular ring: clinical and physiological assessment of pulmonary function following surgical correction.

Twelve children were evaluated 7.1 years (mean) after surgical repair of a vascular ring causing tracheal compression. Nine patients complained of persistent respiratory symptoms, mostly cough, dyspnea, and/or wheezing. Functional evaluation revealed abnormal spirometry and/or lung volumes in seven subjects. Analysis of maximal expiratory-inspiratory flow-volume loops suggested the presence of residual upper airway obstruction in three patients and peripheral airway obstruction in three others. Eleven patients demonstrated bronchial hyperreactivity to histamine.

Adolescent↗