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Biomedical subjects

J G Johansen

Publications and source records attributed to J G Johansen.

At least 37 records · Page 2Linked to original sources

Computed tomography in assessment of myelographic nerve root compression in the lateral recess.

Thirty patients with myelographic shortening of a single nerve root sheath without indentation of the dural sac were studied by CT. Lateral disc herniation was diagnosed by CT in 18 patients. The myelograms of these patients were considered suspicious of disc herniation in three patients, uncertain in seven, and misinterpreted as lateral recess stenosis due to bony encroachment in eight. CT is more reliable than myelography in assessment of the etiology of nerve root compression in the lateral recess.

Adult↗

In vitro testing for the risk of arachnoiditis from myelographic contrast media.

The risk of arachnoiditis from aqueous myelographic contrast media has been assayed reliably only in experimental animals. The effect of contrast media on protein and collagen production by fibroblasts in vitro was studied. Iocarmate, metrizamide, and iopamidol added to the culture medium caused cells to produce more protein and collagen. The degree to which the contrast medium stimulated collagen production correlated with the risk of arachnoiditis from the intrathecal use of the contrast medium. In vitro testing appears to be an effective assay for arachnoiditis.

Arachnoiditis↗

Cervical radiculopathy: computed tomography and myelography compared.

The accuracy of CT in the determination of cervical disk herniation has not been measured as it has in the determination of lumbar disk disease. Cervical myelograms and CT scans of patients with cervical radiculopathy secondary to disk herniation or spondylosis, which was verified by clinical examination, surgery, and in most cases EMG, were evaluated blindly and independently, results were analyzed statistically, and receiver operating characteristic (ROC) curves were calculated. CT without or with the use of intrathecal metrizamide was more accurate than myelography in the identification of lesions that caused cervical radiculopathy. In some patients, CT obviates the need for cervical myelography. With improvement in CT techniques and more experience in interpreting the images, CT will be increasingly important in the evaluation of cervical radiculopathy.

Cervical Vertebrae↗

Retrosomatic clefts: computed tomographic appearance.

A case of bilateral clefts in the pedicles of the L1 vertebra, diagnosed by computed tomography, is presented. The differentiation from other clefts located laterally in the neural arch is briefly summarized, and the possible origin of this entity is discussed. It is improbable that the clefts represent persistent neurocentral synchondroses.

Adult↗

Oral administration of amipaque in obstruction of the colon.

Nine adult patients with complete obstruction of the colon on barium enema examination were evaluated after oral administration of Amipaque. This water-soluble iodinated contrast material proved useful in the diagnosis of obstructive lesion, outlining the narrowed segment and the more proximal colon. There were no side effects.

Administration, Oral↗

Total dural calcification with secondary hyperparathyoidism: a rare entity.

A case of total, dense dural calcification in an adult female patient with secondary hyperparathroidism is presented. The often reported feature in the skull is that of a combination of osteopenia and osteosclerosis giving a granular bone texture described sometimes as "grains of sand" or "salt and pepper" appearance [6]. Extensive dural calcification with this condition has very rarely been reported [2, 3]. The purpose of this paper is to document the existence of the latter in a patient followed up for 19 years.

Calcinosis↗

Dacryocystography with amipaque (metrizamide).

Amipaque is found to be very suitable for dacryocystography because it has a low osmolality and high viscosity, and is in addition the only aqueous contrast medium currently available which in higher concentrations does not cause pain when applied to the conjunctival sac.

Contrast Media↗

Antibacterial effects of metrizoate and metrizamide on bacterial growth in vitro.

Urinary pathogens were exposed in vitro to Isopaque and Amipaque in concentrations of 100 mg I/ml and 260 mg I/ml. Both contrast media in the higher concentration had a slight or negligible bacteriostatic effect on some of the test bacteria. No bactericidal effect was detected. Consequently, radiography of the urinary tract with these two media in the concentrations mentioned does not interfere with the culturing of bacteria from urine samples.

Bacteria↗