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Biomedical subjects

J G Gregory

Publications and source records attributed to J G Gregory.

At least 55 records · Page 3Linked to original sources
PubMed1977

Pharmacologic modification of therapeutic measures used in managing the neurogenic bladder.

In the past 2 years, no supravesical urinary diversions have been done for myelodysplasia at St. Louis University Medical Center. Twenty-six patients with neuropathic bladders have been managed by intermittent catheterization and mechanical devices. The addition of anticholinergic and alpha-adrenergic agents to the therapeutic regimen has markedly increased the numbers of satisfactory results. Based on this group of patients, we are encouraged to believe that supravesical urinary diversion is rarely necessary for the management of both the medical and social problems of the urinary tract associated with myelodysplasia.

Belladonna Alkaloids↗
PubMed1976

Posterior urethral valves.

Twenty cases of posterior urethral valves are reviewed with the presentation of several illustrative cases. Review of the current literature regarding managment of patients is discussed.

Child↗
PubMed1976

Anterior bladder tube in radical retropubic prostatectomy.

Six patients with a minimum of ten months' follow-up have undergone reconstruction of the urethra by anterior bladder tube after radical retropubic prostatectomy; 4 void well and are continent, 1 is incontinent, and 1 has severe stricture.

Aged↗
PubMed1976

Aggressive management of genitourinary complications of renal transplantation.

In the course of 184 renal transplantations performed in St. Louis since 1963, twenty-six minor and twenty-three major complications have occurred. As a result of these complications four kidneys have been lost and 1 patient has died. Aggressive therapy has been utilized in the management of all but two of the major complications and is associated with one death and the loss of two kidneys. On the basis of these results intensive therapy for genitourinary complications is encouraged, and the principles of therapy are discussed.

Adult↗
PubMed1976

Serum lactic dehydrogenase and irreversible renal allograft rejection.

The relationship between serum lactic dehydrogenase (SLDH) values and renal allograft rejection was examined in the dog and in man. Nine dogs with renal allografts and four with autografts had similar maximal elevations of SLDH during the first five postoperative days (mean, 420 +/- 213 and 433 +/- 80 I.U. per liter, respectively). During rejection of the allografts between days 7 and 14 the maximum SLDH was 810 +/- 285 I.U. per liter, and in autografts the peak SLDH was 233 +/- 22 I.U. per liter (p less than 0.01). The isoenzyme pattern of maximum SLDH during rejection was prominent in LDH5 and corresponded with renal tissue LDH isoenzyme composition. In 93 episodes of initial acute human renal allograft rejection reactions, the SLDH peaked above 500 I.U. per liter in 23 cases and remained below 500 I.U. per liter in 70 cases. SLDH levels above 500 I.U. per liter were associated with complete rejection of the kidney in 91 percent of patients and SLDH levels persistently below 500 I.U. per liter corresponded with reversal of rejection reaction in 99 percent of patients (p less than 0.01). Marked SLDH elevation is associated with severe, usually complete renal allograft rejection and may be useful in identifying patients with irreversible rejection reactions.

Animals↗
PubMed1975

Intermittent catheterization in children.

Many children with myelodysplasia are ideal candidates for intermittent nonsterile urethral catheterization to manage urinary incontinence. This method of urinary management becomes no permanent commitment and is preferred by patients and parents to supravesical diversion when successful.

Adolescent↗
PubMed1975

Urologic complications of ileal bypass operation for morbid obesity.

Preoperative, operative and postoperative data from a sampling group of 435 ileal bypass patients have been tabulated and computer-analyzed. Genitourinary disorders other than stone disease have been insignificant. Patients with stones and those without stones have been compared and the significant data tabulated. The incidence of stone disease is 6 per cent. All but 1 stone consisted of calcium oxalate. Oxalate levels were normal preoperatively and elevated in 60 per cent postoperatively. The stone formers are among the heaviest members of the studied population, they have the greatest amount of ileum bypassed and the greatest amount of 1 year weight loss. Correlations between these observations and possible pathways of metabolic stone disease are made.

Body Weight↗