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Biomedical subjects

J G Gamble

Publications and source records attributed to J G Gamble.

57 records · Page 4Linked to original sources

Hip motion changes in hemophilia.

We reviewed early and late motion changes of the hip in 102 hemophiliacs with a mean follow-up of 7 years. Sixty patients (59%) had at least one hip bleed. Sixty-four hips in 49 patients demonstrated at least a 15 degree change in range of motion (ROM) at some time. At final review, only 34 of these 64 hips (53%) lost motion. Patients whose hips lost motion were just as likely to report hip bleeds as those who lost no motion. Twenty hips examined within 2 months of bleeding lost significant motion, but most motion returned within a year. The relationship between hip girdle bleeding and ROM remains obscure.

Adolescent↗

Hypervitaminosis A in a child from megadosing.

Hypervitaminosis A developed in a 2-year-9-month-old boy after his mother gave him 6,338 IU/kg/day vitamin A for 5 months. The clinical features included irritability, xerosis of the skin and mucous membranes, pruritus, bone pain, and loss of ambulation. The bone scan showed involvement of more bones than was apparent on the roentgenograms. A prompt diagnosis depended on an accurate history of excessive vitamin intake, and the serum vitamin A level confirmed the diagnosis.

Bone and Bones↗