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Biomedical subjects

J G Diamond

Publications and source records attributed to J G Diamond.

26 records · Page 2Linked to original sources
PubMed1979

Uveitis: effect of vitrectomy combined with lensectomy.

Combined lensectomy-vitrectomy was performed on 25 eyes in 20 patients with cataracta complicata associated with uveitis from various etiologies. Postoperative follow-up averaged 15 months, with visual improvement in 24 of the 25 eyes. Primary cause of postoperative decreased vision was cystoid macular edema. Operative complications included retinal detachment and choroidal ischemia. The technique employed and the effect of lensectomy-vitrectomy on decreasing the number and severity of recurrent attacks of uveitis are discussed.

Adolescent↗
PubMed1978

Lensectomy and vitrectomy for complicated cataract secondary to uveitis.

Combined lensectomy-vitrectomy was performed on 13 patients (15 eyes) with complicated cataracts from uveitis. Preoperative visual acuities were 20/200 or less for at least one year. The postoperative follow-up period averaged 10.5 months with visual acuities of 20/25 or better in eight eyes, 20/70 in two eyes, and 20/100 to 20/400 in five eyes. The primary cause of decreased vision postoperatively was cystoid macular edema with frequently associated optic disc edema.

Adolescent↗
PubMed1976

6-Hydroxydopamine in treatment of open-angle glaucoma.

In patients with open-angle glaucoma, subconjunctival injection of 6-hydroxydopamine produced chemical sympathectomy and sensitization to topically applied epinephrine. Prior to entry into this study, all patients had intraocular pressures (IOPs) greater than 30 mm Hg and had not responded to maximal medical therapy. The 6-hydroxydopamine was prepared in an ascorbic acid-buffered solution and was well tolerated by the patients. After subconjunctival administration of 6-hydroxydopamine, the mean decrease in IOPs was 50% in the treated eyes and 5% in the contraleteral eyes. Topical administration of 1% epinephrine to eyes injected with 6-hydroxydopamine resulted in a mean fall of IOP of 40% that persisted for as long as three months. Repeated subconjunctival injections of 6-hydroxydopamine renewed the pressure-lowering effects and sensitization to topically applied epinephrine.

Conjunctiva↗
PubMed1975

Vitrectomy in exogenous Candida endophthalmitis.

A case of Candida endophthalmitis was clinically diagnosed three weeks after perforating injury. It was successfully treated with vitrectomy and intravitreal injection of 5 mcg of amphotericin B. A Candida speices was cultured from the vitreous aspirations.

Amphotericin B↗
PubMed1975

The vitrophage in ocular reconstruction following trauma.

We propose a technique using the Peyman vitrophage, a vitrectomy instrument, for the surgical repair of acute and chronic injuries to the anterior segment, such as perforating corneal injuries and complications of cataract extractions. A pars plana approach allows insertion of the vitrophage into the eye with minimal surgical manipulation. All lens, iris, and vitreous remnants are completely removed. We have achieved excellent results in cases of severe eye injuries.

Acute Disease↗
PubMedDate not supplied

Safety evaluation of BSS plus in pediatric intraocular surgery.

An open-label study was conducted to determine the safety of a new intraocular irrigating solution, BSS Plus, when used during pediatric ophthalmic surgery. BBS Plus is a modified glutathione-bicarbonate-Ringer's solution which contains the necessary ions, buffers, and substrates for maintenance of normal cellular metabolism, function, and structural integrity when used as a perfusate during ophthalmic surgical procedures. At three centers, 30 patients undergoing lens aspiration or anterior segment reconstruction using vitrectomy instrumentation were enrolled in this study. Transient postoperative increases in intracellular pressure and internal or external ocular inflammatory signs were seen which were consistent with the trauma produced by the surgical procedure. The solution was judged to be safe when used in these surgical indications.

Adolescent↗