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Biomedical subjects

J G Bieri

Publications and source records attributed to J G Bieri.

At least 73 records · Page 4Linked to original sources
PubMed1970

Determination of alpha-tocopherol in erythrocytes by gas-liquid chromatography.

A method is described for the determination of submicrogram amounts of alpha-tocopherol in 0.5 ml of packed erythrocytes. The alpha-tocopherol in a lipid extract is oxidized to alpha-tocopherylquinone which is separated by thin-layer chromatography, eluted, and quantitated by gas-liquid chromatography. Calculation is based on the recovery of added alpha-tocopherol-(3)H. Erythrocytes from stock rats had an average alpha-tocopherol concentration of 344 micro g/100 ml of packed cells, while for human cells the average was 235 micro g/100 ml. The ratio of red cell to plasma alpha-tocopherol was 0.482 for rat blood, and 0.244 for human blood.

Animals↗
PubMed1969

Survival of germfree rats without vitamin A.

Weanling, germfree rats, transferred to a conventional animal room and fed a vitamin A-deficient diet, died in 23 to 54 days. In contrast, their littermates, kept germfree and on the same diet, survived for as long as 272 days. The rats kept in germfree conditions stopped growing after 1 to 4 months but responded to supplements of retinoic acid.

Animals↗