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Biomedical subjects

J G Barone

Publications and source records attributed to J G Barone.

At least 19 recordsLinked to original sources
PubMed1997

Evaluation of the utility of video-urodynamics in children with urinary tract infection and voiding dysfunction.

OBJECTIVE: To assess the use of video-urodynamic studies (VUDS) in children with urinary tract infection (UTI) and symptoms of voiding dysfunction (frequency, urgency, incontinence), to ascertain whether VUDS significantly assists in diagnosis and deciding treatment. PATIENTS AND METHODS: Over a 16-month period, all children seen at our centre with a UTI in conjunction with previous symptoms suggestive of voiding dysfunction underwent free and pressure-flow VUDS. Forty-two children underwent VUDS and 38 (mean age 9 years, range 4-16, 15 male, 23 female) had sufficient information to be included in the study. RESULTS: All children had a prior history of voiding dysfunction (mean 55 months). Only five patients were found to have reflux and three of these had associated detrusor instability. In addition, 24 of 33 patients who did not have reflux had abnormalities on urodynamic study, the most common problem being detrusor instability in 17 of 24 patients. Other abnormalities included sphincter dyssynergia (five patients), poor bladder compliance (two) and hypersensitivity on bladder filling (three). CONCLUSION: VUDS can provide information about the aetiology of UTI and voiding dysfunction in children that cannot be obtained from any other source. The results of VUDS can be used to select specific treatments, to avoid inappropriate therapy and to identify children who may benefit from follow-up studies despite normal findings on voiding cystourethrography. From these results, we believe that VUDS should be considered for children with UTI and voiding dysfunction.

Adolescent↗
PubMed1996

Cystic renal disease and tuberous sclerosis in infants.

We describe 2 infants who presented with autosomal dominant-like polycystic kidney disease. Evaluation revealed that both children had tuberous sclerosis, with resulting cystic kidney disease. This diagnosis should be suspected in infants who present with bilateral, large renal cysts, and no family history of autosomal dominant polycystic kidney disease.

Female↗
PubMed1996

Diagnosis and management of malignant perirenal schwannoma.

Malignant retroperitoneal schwannoma is an extremely rare tumor, with only six cases previously reported occurring in the perirenal space. We herein report the seventh case. A 50-year-old woman presented with an abdominal mass suggestive of renal cell carcinoma by standard preoperative evaluation. The tumor required surgical exploration and pathologic evaluation for diagnosis. The final histologic diagnosis was made with the aid of electron microscopy and immunohistochemical staining with antibodies for S-100 protein.

Basement Membrane↗
PubMed1995

Symptomatic tumors affecting the urinary tract in children with neurofibromatosis.

PURPOSE: We determined the need for urological screening in children with neurofibromatosis. MATERIALS AND METHODS: Of 96 children with neurofibromatosis treated at our institution 6 (6.2%) had a symptomatic tumor that affected the urinary tract. RESULTS: There were 5 plexiform neurofibromas and 1 prostatic rhabdomyosarcoma. Five children had a palpable abdominal mass and 3 required urinary diversion. CONCLUSIONS: Since most morbidity resulted because tumors were advanced by the time symptoms developed, we suggest that children with neurofibromatosis be screened annually with medical history, physical examination, urinalysis and serum chemistry studies for tumors that affect the urinary tract.

Adolescent↗
PubMed1995

Vena cava resection during post chemotherapy lymphadenectomy for testis tumor.

Two patients underwent retroperitoneal lymphadenectomy after chemotherapy for non-seminomatous germ cell testis tumor. A dense desmoplastic tissue reaction between the infrarenal vena cava and perivascular lymphatic tissue prohibited removal of the nodal packet from the vena cava in both cases. We herein discuss two techniques for vena cava resection in these difficult cases.

Adult↗
PubMed1994

Etiology of acute urinary retention following benign anorectal surgery.

The etiology of acute urinary retention following benign anorectal surgery is unknown. We performed bedside urodynamic evaluation on nine patients who developed acute urinary retention after benign anorectal surgery. A bladder contraction was demonstrated in all patients, which suggests that the retention is due to bladder outlet obstruction and not bladder acontractility. These findings have important implications for preventing and treating acute urinary retention following anorectal surgery for benign disease.

Acute Disease↗
PubMed1992

Urodynamics in the early stages of spinal cord compression from prostate adenocarcinoma.

Acute urinary retention developed in 2 patients with a history of prostate cancer. Urodynamic evaluation revealed autonomic dysfunction, which contrasted with a prior urodynamic study, indicating a possible spinal lesion. Radiographic evaluation led to early diagnosis and treatment of spinal cord compression from metastatic prostate adenocarcinoma. We discuss the diagnostic role of urodynamics in such cases.

Adenocarcinoma↗
PubMed1992

Writing competition winner: Robert Wood Johnson pouch.

Traditional treatment for muscle invasive bladder cancer requires the creation of an abdominal stoma for urinary diversion. The authors report a technique for orthotopic bladder substitution. This paper was the 1991 winner of the MSNJ Writing Competition.

Aged↗
PubMed1992

Diagnosis and staging of bladder cancer.

The need for prompt diagnosis and accurate staging of bladder cancer cannot be over-emphasized, as delays in diagnosing the tumor are clearly associated with a poor prognosis. Accurate staging using the American Joint Committee system is essential if clinicians are to compare the results of different therapies.

Biopsy↗