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Biomedical subjects

J Fukuda

Publications and source records attributed to J Fukuda.

At least 199 records · Page 11Linked to original sources
PubMed1975

Case report. Two cases of pulmonary hypertension with Raynaud's phenomenon. Primary pulmonary hypertension and systemic lupus erythematosus.

Two cases of hypertensive pulmonary vascular disease with Raynaud's phenomenon are reported. One is a 32-year-old housewife of primary pulmonary hypertension with some immunological disorders and the other is a 28-year-old female of systemic lupus erythematosus. It may be considered that some immunological process could play a role in the etiology of some cases of primary pulmonary hypertension and the relationship of pathogenesis between these 2 cases was discussed.

Adult↗
PubMed1974

Membrane currents carried by Ca, Sr, and Ba in barnacle muscle fiber during voltage clamp.

Membrane currents associated with voltage clamp of the giant muscle fibers of a barnacle, Balanus nubilus, were analyzed in terms of currents of the Ca and K channels. Although the activation of the K channel occurs more slowly than that of the Ca channel, both currents show a significant temporal overlap. The currents carried by Ca(++), Sr(++), or Ba(++) through the Ca channel were compared under the conditions at which this overlap was the least. When only one divalent cation is present in the solution, Ba(++) carries more current than Ca(++) or Sr(++) and the sequence of the current is Ba > Sr approximately Ca. When the external solution contains a relatively high concentration of Co(++), which is a blocking agent for the Ca channel, inversion of the sequence occurs, to Ca > Sr > Ba. This is due to the fact that the blocking effect differs depending on which ion carries current through the Ca channel. The Ba current is most sensitive and the Ca current is least affected. Ba suppresses the current of the K channel, independently of its current-carrying function through the Ca channel.

Animals↗