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Biomedical subjects

J Friberg

Publications and source records attributed to J Friberg.

95 records · Page 6Linked to original sources
PubMedDate not supplied

Role of computed tomography and mediastinoscopy in preoperative staging of lung carcinoma.

One hundred fifty-three patients with bronchogenic carcinoma were evaluated prospectively by CT and mediastinoscopy. Nodes larger than 5 mm were considered potentially metastatic. All results were correlated with surgical findings. Computed tomography is more sensitive (89%) in the detection of mediastinal metastases than mediastinoscopy (67%). Computed tomography has a poor predictive value (47%); however, a negative examination is highly accurate (89%). Within a group of 100 node sites, 72% of the nodes involved by tumor were larger than 1 cm in diameter. Squamous cell carcinoma and adenocarcinoma have the highest percentages of sensitivity by CT. The very low incidence of metastatic involvement in nodes under 5 mm allows one to forego mediastinoscopy in the presence of a negative CT.

Adenocarcinoma↗
PubMedDate not supplied

Effects of progesterone on postoperative adhesion formation in hysterectomized rabbits.

Progesterone has been reported to have an antiinflammatory as well as immunosuppressive effect, and may prevent adhesion formation. In this study, nine treated and seven control rabbits were randomly selected for either pre- and postoperative progesterone treatment or no treatment. All rabbits underwent hysterectomy, focal peritoneal denudation, and intraabdominal instillation of suspended talc. Adhesion formation was evaluated 1 month postoperatively during repeat exploratory laparotomy. Progesterone-treated and control rabbits did not show any significant difference overall in the incidence of adhesion formation. Subgrouping of adhesion formation into adhesions formed by major surgical tissue trauma or minor peritoneal damage revealed a beneficial effect of progesterone in the reduction of only minor adhesion formation.

Animals↗