Search PubMed⌕ Search

Biomedical subjects

J Frexinos

Publications and source records attributed to J Frexinos.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

[Incidence of colorectal cancer in the Haute-Garonne Department. Evaluation of 2 years of registration (1982-1983)].

During a two-year period ending in 1983, 882 colorectal cancers (CRC) were diagnosed among 820,000 residents in the department of Haute-Garonne (France). The age-standardized incidences were 24.3 and 19.1 per 100,000 in men and 15.2 and 9.5 per 100,000 in women, for colon and rectal carcinomas respectively. The Haute-Garonne population-based registry showed one of the highest rates of risk of CRC in Europe. A relatively high incidence of rectal cancer, a marked male preponderance particularly in left-side colon cancers, and a higher mean age in female patients (67.1 +/- 11.6 and 70.2 +/- 11.9 (p less than 0.001] was observed. Distribution of CRC within the department was heterogeneous. Although there was no significant difference between urban and rural areas, some regions showed a higher incidence (the "Volvestre" in both sexes and the "Riviere" in women) whereas the "Pyrénées Centrales" showed a lower incidence in women only. CRC was often diagnosed at an advanced stage (Dukes A: 26.1 p. 100, Dukes B: 22.2 p. 100, Dukes C: 27.4 p. 100, visceral metastases: 24.4 p. 100 especially in women (p less than 0.02). Among symptom-free patients (4.5 p. 100) cancers limited to the colonic wall represented 71.4 p. 100 of cases. This suggests that prognosis of CRC could be improved by routine screening of healthy populations. Surgery was performed in 91 p. 100 of colonic cancers and 85 p. 100 of rectal cancers but was considered to be curative in only 55 p. 100 of all cases.

Adult↗