Aberrant left pulmonary artery.
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Biomedical subjects
Publications and source records attributed to J Fleming.
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Haemodynamic studies have been performed in 9 patients whose blood pressures had been satisfactorily controlled with oral propranolol for 7 to 29 months. A postural drop of blood pressure or a fall of blood pressure on exercise did not occur. Pulse rate and cardiac output were below normal at rest and on exercise; peripheral resistance was high. The results are similar to those obtained in a comparable group of hypertensives after acute administration of propranolol. These findings are discussed in relation to the mode of action of propranolol in hypertension.
Review of the 74 patients undergoing aortic valve replacement with a Starr-Edwards ball-valve prosthesis between October 1963 and December 1967 showed that 16 died during surgery or within the first month after operation, usually owing to myocardial failure; and there were nine late deaths. The remaining patients developed few major complications, and the long-term results of operation are considered satisfactory, no patient being grossly incapacitated and most of them are leading active, symptom-free lives.
Studies in 17 hypertensive patients showed that the electrocardiographic features of T-wave inversion and S-T segment depression distinguish those patients with higher systolic blood pressures. They do not indicate impaired cardiac function.
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