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Biomedical subjects

J Fleming

Publications and source records attributed to J Fleming.

At least 181 records · Page 10Linked to original sources

Haemodynamic studies in hypertensive patients treated by oral proranolol.

Haemodynamic studies have been performed in 9 patients whose blood pressures had been satisfactorily controlled with oral propranolol for 7 to 29 months. A postural drop of blood pressure or a fall of blood pressure on exercise did not occur. Pulse rate and cardiac output were below normal at rest and on exercise; peripheral resistance was high. The results are similar to those obtained in a comparable group of hypertensives after acute administration of propranolol. These findings are discussed in relation to the mode of action of propranolol in hypertension.

Adult↗

Long-term results of aortic valve replacement with the Starr-Edwards valve.

Review of the 74 patients undergoing aortic valve replacement with a Starr-Edwards ball-valve prosthesis between October 1963 and December 1967 showed that 16 died during surgery or within the first month after operation, usually owing to myocardial failure; and there were nine late deaths. The remaining patients developed few major complications, and the long-term results of operation are considered satisfactory, no patient being grossly incapacitated and most of them are leading active, symptom-free lives.

Adolescent↗

Significance of electrocardiographic changes in hypertension.

Studies in 17 hypertensive patients showed that the electrocardiographic features of T-wave inversion and S-T segment depression distinguish those patients with higher systolic blood pressures. They do not indicate impaired cardiac function.

Adult↗