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Biomedical subjects

J Fleischer

Publications and source records attributed to J Fleischer.

At least 55 records · Page 3Linked to original sources

[Characterization of functional disorders of bone marrow by measuring chemiluminescence].

It is reported on first experiences with measurements of chemiluminescence on the bone marrow. Suspensions of the bone marrow show a spontaneous chemiluminescence which can be stimulated by Zymosan. Haematological diseases and changes of the bone marrow under influence of the cytostatic therapy react on the behaviour of chemiluminescence. The size of the changes possibly allows of conclusions to the behaviour of the regeneration of the bone marrow.

Antineoplastic Combined Chemotherapy Protocols↗

Investigations of factors influencing the prognosis of colon cancer.

Six hundred sixty patients from Downstate and Hackensack Medical Centers were restaged and reviewed to establish correlations with survival using Cox's proportional hazards model. Age, sex, tumor size, and total nodes examined in patients with involved nodes did not correlate with survival. Tumor depth, number of involved nodes, and total nodes examined in patients with uninvolved nodes did correlate with survival. Patients with metastatic invasion into an adjacent organ with uninvolved nodes had an excellent 5 year survival rate compared with patients who had full-thickness invasion into the serosa with uninvolved nodes. These observations need to be confirmed. The relationship of some of these factors to currently used staging systems has also been discussed.

Colonic Neoplasms↗

[Prognosis of non-Hodgkin's lymphomas in the Dresden district with special reference to combined radio-/chemotherapy].

The total population affected with non-Hodgkin's lymphoma and treated by means of radiotherapy or combined radio-chemotherapy between 1960 and 1985 at the Medical Academy Dresden was analysed as to prognosis. 247 patients were classified according to the previous German scheme, 79 were subdivided on the basis of the recommendations laid down in the Kiel classification. The remission rates and survival curves achieved will stand out the comparison with international literature (remission rates of the low malignancy group amounted to 85.3 p.c. and those of the high malignancy group to 80.0 p.c.; the 5-years survival rates of the low malignancy group amounted to 61.9 p.c. and those of the high malignancy group to 41.7 p.c.). The influence of histology, clinical stage and involvement of organs is discussed on the basis of our results and informations obtained in literature. Our analysis confirms the high importance which must be attached to a common radiologic-internal outpatient-department for co-ordinating the diagnostic and therapeutical programme.

Antineoplastic Combined Chemotherapy Protocols↗

[The effect of Neythumun in comparison with 2-cyanoethylurea on the white blood count of the rat].

The stimulation effect of Neythymun-Sol f+k (Nthy) and 2-Cyanethylcarbamide (CEC) on the leucocytopoesis was studied in 30 Wistar rats and a moderate but significant increase in the total number of leucocytes was found. The increase produced by CEC didn't prove significantly higher than that by Nthy. After 32 d the blood count showed a substantial difference concerning the neutrophils with an increase from 3000 to 9000 without deviation to the left, which was found only under Neythymun. This compound seems to be useful as a stimulator for the neutrophilic leucocytopoesis.

Animals↗