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Biomedical subjects

J Flament

Publications and source records attributed to J Flament.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

Impact of various red cell concentrate preparation methods on the efficiency of prestorage white cell filtration and on red cells during storage for 42 days.

BACKGROUND: White cell (WBC) reduction prior to storage of red cell (RBC) concentrates may reduce the incidence of HLA alloimmunization and may improve the quality of stored RBCs. STUDY DESIGN AND METHODS: An integrated WBC-reduction filter system was tested after various RBC preparation procedures (from whole blood), and the influence of filtration on RBCs during storage for 42 days was investigated. Four additive system RBC preparation protocols were used. Units prepared from conventional triple blood bags were held for 4 to 6 hours at 22 degrees C, and then the RBCs were separated via a hard spin and filtration, performed immediately (Group 1) or after 18 hours' storage at 4 degrees C (Group 2). Units prepared from a top-and-bottom collection system were held at 22 degrees C for 4 to 6 or 22 to 24 hours; the centrifuged RBCs were filtered immediately after preparation (Groups 3 and 4, respectively, by holding time). WBC reduction and filtration time were analyzed. The impact of WBC filtration on pH, hemolysis rate, hemoglobin content, ATP, potassium glucose, and lactate was investigated weekly during storage for 42 days. RESULTS: Filtration reduced the mean WBC count by 3 to 4 log10, to 0.19 +/- 0.25 x 10(6), regardless of the RBC preparation method. Mean filtration times differed significantly between the groups and were longest for Group 1. Besides hemolysis and pH values, which were greater in all filtered units, no major differences were found in filtered and unfiltered RBCs during the storage interval. CONCLUSION: The efficiency of prestorage WBC filtration of RBCs was unaffected by the preparation procedure. However, the filtration time for RBCs freshly prepared in the conventional triple blood bag system without buffy-coat depletion was unacceptable. No major metabolic differences between filtered and unfiltered RBCs during 42 days of storage were found.

Blood Preservation↗
PubMedDate not supplied

[Poisoning of retinal pigment epithelium by deferoxamine. A case report].

A patient undergoing hemodialysis was treated intravenously with desferrioxamine (3 g) for an aluminum encephalopathy. He presented a sudden xanthopsia with visual loss. Fundus examination showed diffuse macular irregular pigmentary disturbances. We discuss current knowledge and possible pathogenesis of these observations published since 1983. Awareness of the side effects of desferrioxamine implies an ophthalmologic follow up similar as chloroquine.

Aged↗
PubMedDate not supplied

[Pseudo-exfoliative glaucoma in eastern Algeria. Clinical study].

The authors present the results of a study concerning 656 patients, over 40 years old, presenting a glaucoma, or a Capsular pseudoexfoliation, or both. These patients have been admitted at the Annaba Ophthalmology Clinic between September 1st, 1984 and September 1st, 1987. Frequency, age, sex, glaucoma-CPE association, opening and pigmentation of the iris-cornea angle, as well as the level of intraocular pressure, are studied. It turns out that the pseudoexfoliative glaucoma represents 53% of all glaucoma, that it is a particular form of primitive glaucoma, generally with open angle, of severe evolution, but that it can be controlled with an adequate treatment, often surgical.

Adult↗
PubMedDate not supplied

[Clinical applications and critical evaluation of helium-neon laser interferometry].

Exploration of macular function in patients opaque media has been performed routinely with Helium-Neon Laser interferometry for more than 5 years. Our results in patients with cataract, macular diseases, retinal detachment and functional amblyopia are reported. Accurate correlations, overestimations and underestimations are differentiated with special emphasis on overestimations.

Amblyopia↗
PubMedDate not supplied

[Interocular accommodative disparities: asymmetry and/or paresis?].

Description of interocular accommodative disparities about 3 cases of young patients, whose occupations require an excellent stereopsis in near vision. Is is a paresis, an asynergy or a constitutional asymmetry? In order to delimit this pathology, the accommodative power of each eye has been measured on a reference population including 100 subjects aged 20 to 35 years. The suitable correction of this anomaly, allows an exact compensation and the recovery of a normal functional comfort.

Accommodation, Ocular↗
PubMedDate not supplied

[Pseudo-exfoliative fibrillopathy in eastern Algeria. Epidemiologic and statistical study].

The systematic examination of 1440 patients of more than 40 years old divided into two groups of 607 hospitalised patients and 833 consultants has revealed the exceptionally high frequency of the pseudo-exfoliative disease in the East of Algeria. In fact this syndrome is find in 25% of the cases. The analysis relates the different epidemiology criteria: age, topography, geographic factors and biomicroscopic characters. The association to the glaucoma of this syndrome forms the subjects of a study which details particularly its frequency, its different clinical forms, the factors of the intraocular pressure and the evolution under treatment. The authors have compared this study to those wHich have been described in literature.

Adult↗