Search PubMed⌕ Search

Biomedical subjects

J Fichter

Publications and source records attributed to J Fichter.

25 records · Page 2Linked to original sources
PubMed1990

[Diagnosis of lung function in patients with ankylosing spondylitis].

In a group of 55 men of 18 to 58 years of age who were suffering from ankylosing spondylitis, changes in lung function were analysed by measuring the static parameters and by differentiating between the thoracic and abdominal parts in breathing at rest and under stress, using CO2 rebreathing. In accordance with the reduction in vital capacity, the thoracic share is restricted already at rest. At rest, there is compensation via the abdominal compartment, in contrast to the stress in CO2 rebreathing in which the abdominal part does not compensate.

Adolescent↗
PubMed1990

[Measuring airway resistance with the oscillation method: Oscillaire and Custovit].

Measurement of airway resistance by the oscillation method was done on the one hand by means of the pseudo random noise method (Oszillaire, Jones Company) multifrequence from 6 to 26 Hz in steps of 2 Hz. In addition, the oscillatory resistance was also determined by means of the custo vit (Customed), the frequency of the pump producing the oscillation being variable so that measurements were carried out successively at different frequencies. 2 different versions were tested. In the first version the resonance frequency was measured and then monofrequently the pertaining resistance. In another version the impedance (total airway resistance) was measured at different frequencies in a frequency range between 6 and 20 Hz in steps of 2 Hz with both methods. Additionally, the airway resistance was also measured by bodyplethysmography. A clinical study was carried out in a group of 21 healthy subjects and 34 obstructed patients with asthma bronchiale and chronic obstructive lung disease. When measuring the airway resistance with the custo vit at the frequency of resonance there was poorer differentiation between normal and obstructed subjects compared to a measurement at a fixed frequencies yielded comparable values for both methods.

Airway Resistance↗
PubMed1989

Resistance measurement in normal and obstructed excised human lungs by means of the interrupter method.

In 6 normal and 7 obstructed excised human lungs the interrupter resistance (APTA, Jaeger Company) with an airway occlusion period of 100 ms was determined, by measuring the equivalent of the alveolar pressure at the end of the occlusion period. To check the pressure equilibration between the tracheal pressure and the alveolar space, catheters were put in the most peripheral layer of the lung. The lungs were ventilated in an artificial thorax. The airway resistance determined from the transbronchial pressure difference by the catheters was taken as a reference. Compared with the reference method, an overestimation of the airways resistance by the interrupter technique in normal lungs was found which was caused by an overshoot of the pressure equilibration during the occlusion period. In contrast, in severely obstructed lungs the pressure equilibration was not complete which led to an underestimation of the airways resistance by the interrupter technique. The best approximation of the airways resistance by the interrupter method was found in lungs with a low degree of obstruction.

Airway Obstruction↗
PubMed1989

[Oscillatory measurement of airway resistance with the custo vit in comparison with Oscillaire and whole body plethysmography].

The airway resistance was measured by forced oscillation technique with the pseudorandom noise method (Oscillaire, Jones) at multiple frequencies ranging from 6 to 26 Hz in steps of 2 Hz (Ros1). In addition, the oscillatory resistance was determined with the custo vit unit (Customed), the frequency of the pump generating the oscillation being selectable (Ros2), so that successive measurements were made at different frequencies. The custo vit is available in different technical versions. With the first version, a single frequency was used to measure the resonance frequency and to determine the associated resistance. By a different version, the impedance of various frequencies in the range between 6 and 16 Hz in steps of 2 Hz were determined for both methods. Finally, using 3 frequencies (8, 12 and 16 Hz) the total impedance was differentiated into resistance and reactance. In addition, the airway resistance was determined by bodyplethysmography. A clinical study was performed in a group of 21 healthy subjects and 34 patients with bronchial asthma and chronic obstructive lung disease. With both methods, the correlation of the resistance, determined by forced oscillation technique and Raw showed decreasing values with increasing frequency. In the case of the measurement of the airway resistance with the custo vit at resonance frequency, a poorer differentiation between normal subjects and patients with obstruction was obtained as compared with measurements made at a fixed frequency of 6 Hz. This is the result of a shift in the resonance frequency towards higher frequencies in the case of an obstruction, and the simultaneously occurring frequency-dependence of the resistance. A comparison of the impedance at different frequencies revealed comparable values with both methods, but in the case of the differentiation into resistance and reactance, it was seen that higher resonance frequencies were established with Ros1 as compared with Ros2 in the case of obstruction.

Airway Resistance↗
PubMed1987

Human chorionic gonadotropin, estriol, and testosterone changes in two pregnancies with hyperreactio luteinalis.

A case of hyperreactio luteinalis is presented with measurements of human chorionic gonadotropin, total and free testosterone, and estriol throughout two term pregnancies. Ovulation induction with menotropins resulted in one spontaneous first-trimester abortion, one singleton term pregnancy, and 1 triplet pregnancy that converted to a singleton term pregnancy after spontaneous degeneration of two fetuses in the first trimester. During the first term pregnancy, levels of human chorionic gonadotropin peaked at 34 weeks of gestation (169,000 mIU/ml) and levels of total testosterone peaked at the same time (1777 ng/dl). Free testosterone (16.6 ng/dl) and estriol (10.8 ng/ml) reached their peak at 36 weeks of gestation. During the second term pregnancy, peak values of human chorionic gonadotropin (150,900 mIU/ml) and total testosterone (870 ng/dl) occurred at 10 and 5 weeks of gestation, respectively, before two fetuses of a triplet pregnancy degenerated.

Adult↗
PubMed1980

[Discriminant analysis in the quantitative evaluation of lung scintigrams (author's transl)].

Lung scintigrams made with 99mTc-MAA in a group of patients and a control group were compared and classified by a discriminant analysis based on two regional methods and several parameters for quantitative characterisation of the regions. Improved results are gained by a regional division of the lung orientated in the pulmonary lobes and segments and by combining several parameters.

Analysis of Variance↗