Biomedical subjects

J Ferrero Arias

Publications and source records attributed to J Ferrero Arias.

9 recordsLinked to original sources

PubMed1991

[Prevalence of several neurological diseases in the central provinces of the Iberian Peninsula in eighteen-year-old males].

The prevalence of several neurological diseases has been estimated in eighteen-year-old males living in the central provinces of the Iberian Peninsula (Avila, Badajoz, Caceres, Ciudad Real, Cuenca, Guadalajara, Madrid, Toledo and Segovia). To this end, the yearly recruitment census and the neurological evaluations in the recruits form each year between 1985 and 1989 were used. The yearly prevalence rates (per 10,0000) were evaluated for an overall population of 235,976 recruits. Particularly reliable and accurate, among the observed rates, were those related to epilepsy (513), multiple sclerosis (7.6), hereditary ataxias (10.6), neurological form of Wilson's disease (1.7), Tourette's disease (1.3), syringomyelia (0.9), focal neuropathies (74.6), diffuse neuropathies (17.8), myotonic dystrophy (5.5), congenital myotonia (4.7), myasthenia gravis (3.0), hypokalemic periodic paralysis (1.7), and myopathies as a whole (31.8). The possible usefulness to carry out studies with this outlook and the type of conditions more adequate for them are discussed.

Adolescent↗

PubMed1990

[Risk factors in atherothrombotic cerebral infarct. Are there differential risk profiles in extensive cortical infarct and lacunar infarct? A case-control study].

A study of cases and controls was performed to define the factors associated with nonembolic cerebral infarction and to compare the risk profiles of extensive cortical infarction (ECI) to those of lacunar infarction (LI). One hundred and four patients with ECI were matched with 71 patients with LI and with 90 controls. Although the initial analysis disclosed multiple factors associated with cerebral infarction, the analysis with control of the factors revealed that the only factors related with the occurrence of atherothrombotic infarction were: arterial hypertension [odds ratio (OR) = 6.8], diabetes mellitus (OR = 5.6), ischemic cardiac disease (OR = 5.5), increased hematocrit value (OR = 3.0), and atherogenic lipids in patients without arterial hypertension nor diabetes. Diabetes appeared as the only factor specifically associated with LI when compared with ECI (OR = 2.1). This study supports the following conclusions: 1) the risk profile of nonembolic cerebral infarction is concise and intelligible, 2) the possible role of arterial hypertension in the genesis of LI was not confirmed, and 3) diabetic microangiopathy may be implicated in the genesis of most of LI. Conclusions from this retrospective study should be taken as an interpretation of the results since some restriction in the sensitivity of the data analysis was deliberately introduced.

Aged↗

PubMed1990