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Biomedical subjects

J Ferrando

Publications and source records attributed to J Ferrando.

At least 91 records · Page 5Linked to original sources

Primary ovarian pregnancy with intrauterine device in situ.

A case of primary ovarian pregnancy associated with an intrauterine device in a multipara taking thyroglobulin is reported. The clinical signs and symptoms were identical to those of any ectopic pregnancy with tubal rupture and hemoperitoneum. The final diagnosis was based on the histopathological findings. The literature is reviewed and the association between IUD and ovarian pregnancy is discussed.

Adult↗

[Juvenile xanthogranuloma in a flat xanthoma].

A case of juvenile xanthogranuloma located on a plane xanthoma plaque in the left flank of a seven months old child is reported. Histologically we observe a typical pattern of JXG in the center of the lesion and foamy cells exclusively around the capillary vessels in the peripheric areas of the lesion. We consider that the same etiopathogenic mechanisms implicated in the JXG will produce the clinical and histologic appearance of plane xanthoma around it.

Female↗

[Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions].

A topical clinical trial with preparations containing urea and sodium pyruvate has been made. It was used for diverse hyperkeratotic skin conditions (psoriasis, xerosis, pityriasis rubra pilaris, stuccokeratosis, seborrheic dermatitis, stasis dermatitis, pityriasis lichenoides chronica). A month later a clinical improvement was evident in all cases except in pityriasis lichenoides.

Administration, Topical↗

[Merkel-cell tumor].

A Merkel cell tumor of the preauricular region in a seventy-seven years old woman is described. Histological, electronmicroscopic and tissular hormonal studies, were made. From the pathological point of view, a nodular and trabecular pattern of oval or elongated cells with poor basophilic cytoplasma is characteristic. Large nuclei with irregular, oval prominent nucleoli are also present. Electron microscopy shows oval and polygonal cells of irregular nuclei with one or multiple prominent nucleoli. In the cytoplasm of these cells, microfilaments and dense core granules with clear halo are found. The tissular hormonal determinations were normal. Two years after the surgical treatment, the patient remains asymptomatic.

Adenocarcinoma↗

[Keratosis follicularis spinulosa decalvans (Siemens' syndrome) associated with other abnormalities].

Keratosis follicularis spinulosa decalvans (ichthyosis follicularis or Siemens's syndrome) is considered a general form of keratosis pilaris decalvans. Localized types are keratosis pilaris atrophicans and atrophoderma vermicularis. A case of this unusual process is presented. Clinical, histological and scanning electron microscopic studies of the hair were performed. Clinically, a generalized hypotrichosis with hyperkeratotic follicular plugs is observed; especially in the scalp and the eyebrows. Other interesting clinical findings were cutis hyperelastica, gingival hypertrophy, mongoloid palpebral fissures, big pinnae and clinodactyly of the 5th finger. From the histological point of view we observed follicular plugging, dystrophic pilosebaceous follicles, absence of sebaceous glands, perifollicular fibrosis and minimal lymphomonocytic infiltrate. Scanning electronmicroscopy shows a brittle hair with cuticular abnormalities. Siemens's syndrome can be considered a specific pilosebaceous dysplasia because the absence or hypoplasia of sebaceous glands; which produces follicular hyperkeratosis and pilar atrophy with perifollicular fibrosis and alopecia.

Abnormalities, Multiple↗

[Polypoid pseudosarcoma of the tongue].

Polypoid pseudosarcoma (PP) is a rare type of squamous-cell carcinoma of mouth, fauces and larynx with sarcoma-like reaction. Clinically PP is characterized by large pedunculated or sessile masses of rapid growing. This tumour recurs easily but rarely provokes metastasis. A case of polypoid pseudosarcoma of the tongue is reported. Differential diagnosis with spindle-cell carcinoma can be made following the criteria: a) the frequency and the sarcomatous appearance of the metastasis in the spindle-cell carcinoma, while PP rarely provokes metastasis which have a squamous-cell pattern; b) the gradual transition within the epithelial and the sarcomatous aspects in the spindle-cell carcinoma, not present in PP; and c) the presence of tonofilaments and desmosomes in the sarcomatous cells of the spindle-cell carcinoma, which lack in the sarcoma-like masses of PP.

Aged↗

[Woolly hair. Apropos of 5 cases].

Five cases of Woolly hair, three generalised, and two localised are reported. On the first two, we carried out trichogrammes which were studied with polarized light, and on all five, SEM (Scanning Electron Microscopy). The data obtained coincided with previous descriptions (Pseudomonilethrix images, Pili torti, Trichorrhexis nodosa, reduced hair diameter, oval section following transversal cut, and a wavy-line disposition), although we emphasize the smaller number of layers of cuticle cells following the transversal cut, and the presence of Trichonodosis, not previously refered.

Child↗

Specific cutaneous manifestations of Waldenström's macroglobulinaemia. A report of two cases.

Patients affected by Waldenström's macroglobulinaemia may rarely present specific cutaneous manifestations. The violaceous plaques or tumours infiltrated by lymphoplasmocytoid cells, and the pink, translucent, shiny papules composed of deposits of hyaline monoclonal IgM possess definite clinico-pathological characteristics that may permit the diagnosis before any other data were available. The immunopathological and ultrastructural features of these lesions are described.

Aged↗