Search PubMedSearch

Biomedical subjects

J F Wasserman

Publications and source records attributed to J F Wasserman.

4 recordsLinked to original sources

Biomechanics of the normal and abnormal hip joint.

Static analysis of the canine hip has given some insight to the nature and trend of the force and subsequent stress that is normally applied to the joint. Using the static model, the magnitude and direction of force and stress worsens in the hip with the anatomic and stability changes associated with CHD. More sophisticated dynamic models that take into account unbalanced forces and moments with the resultant motion are needed to better understand the mechanics of the hip joint.

Animals

Ultrasonic B-scan echoarteriographic imaging of experimentally induced thrombi in dogs.

Ultrasonic echoarteriography is a noninvasive method of visualizing extracranial arteries in health and disease. The real-time echoscanning device developed at the University of Cincinnatti utilizes a 5-MHz (center frequency) pulse-echoimaging system. B-mode pictures of the tissues studied are obtained and displayed on a video screen, real-time operation being provided by the scanning mechanism operating at 30 frames per second. In our experiments internal arterial damage produced by surgically scraping the intima induced experimental thrombosis in nine carotid in nine carotid and three femoral arteries in dogs. Where pathologically demonstrated, the thrombi were demonstrated by ultrasonic echoarteriography in every instance. Echoarteriography seemed more sensitive than contrast arteriography in the detection of a partially occlusive thrombus.

Animals

Electronic stethoscope for detection of cerebral aneurysm, vasospasm and arterial disease.

A specially designed acoustic stethoscope electronic-computer-analysis system has repeatedly detected and identified angiographically demonstrated anteriorly located intracranial aneurysms by their characteristic signals. The system has detected and measured clinically significant disease in the carotid siphon and bifurcation, even in cases with normal angiograms, and has recorded the onset and disappearance of cerebral vasospasm. Our data suggests that an aneurysm may act as a flexible Helmholtz resonator, possibly being driven by vortex shed or turbulence. Our goal is the development of a safe, non-invasive method by which the physician could investigate warning symptoms of aneurysms, cerebral vasospasm, and arterial disease in order to recommend preventive surgery or medical treatment early before the patient's condition might deteriorate. Individual cases, falsely positive and negative results are discussed.

Adult