Search PubMed⌕ Search

Biomedical subjects

J F Wade

Publications and source records attributed to J F Wade.

7 recordsLinked to original sources

Far lateral disc herniations treated by microscopic fragment excision. Techniques and results.

STUDY DESIGN: This was a retrospective review of a consecutive series of patients who underwent excision of far lateral disc herniations by a paraspinal, muscle-splitting incision that spares the facet. OBJECTIVE: The authors describe the surgical technique in detail and review the results of surgical treatment. SUMMARY OF BACKGROUND DATA: As the lumbar nerve roots exit the intervertebral foramen, they once again lie in juxtaposition to an intervertebral disc and are susceptible to compression with subsequent radiculopathy. Radiculopathy caused by disc herniations in this area is less common, and the anatomy is less familiar to spinal surgeons than that of paramedian disc herniations. The involved root can be approached by a transfacetal approach or by a muscle-splitting approach that spares the facet. METHODS: Thirty-one consecutive patients had undergone the muscle-splitting approach to far-lateral disc herniations. Twenty-five (80.6%) of these patients were available for evaluation at a minimum of 2 years after surgery. Evaluation consisted of history, pain questionnaires, visual analogue scales, physical examination, and plain radiographs. RESULTS: Twelve patients (48%) had excellent results, eight (32%) had good, and five (20%) had either fair or poor results. Low back pain and dysesthesias were causes of unsatisfactory results. No radiographic sign of instability developed postoperatively. CONCLUSION: The anatomy of the nerve root lateral to the pedicle and our technique for microscopic excision of herniated disc fragments lateral to the facet are described. Our overall results were encouraging. The described microscopic technique will hopefully minimize dysesthetic pain that appears to be the result of the manipulation of the dorsal root ganglion.

Adult↗

Infiltrative and interstitial lung disease in the elderly patient.

The interstitial lung diseases encompass a wide array of inflammatory and fibrotic processes that produce a significant amount of morbidity in the elderly. Diagnosis usually requires a systematic approach and often requires lung biopsy. Treatment typically involves the use of immunosuppressive dosages of corticosteroids or cytotoxic agents. The use of these medications in the elderly demands meticulous, close follow-up because side-effects can be substantial.

Adrenal Cortex Hormones↗

Diesel asthma. Reactive airways disease following overexposure to locomotive exhaust.

While some of the gaseous and particulate components of diesel exhaust can cause pulmonary irritation and bronchial hyperreactivity, diesel exhaust exposure has not been shown to cause asthma. Three railroad workers developed asthma following excessive exposure to locomotive emissions while riding immediately behind the lead engines of caboose-less trains. Asthma diagnosis was based on symptoms, pulmonary function tests, and measurement of airways hyperreactivity to methacholine or exercise. One individual's peak expiratory flow rates fell in a work-related pattern when riding immediately behind the lead diesel engine. None had a previous history of asthma or other respiratory disease and none were current smokers. All three developed persistent asthma. In two cases, physiologic abnormalities suggesting reversible restriction were observed. This is the first report implicating diesel exhaust as a cause of reactive airways disease.

Adult↗

Use of modified subcutaneous right-atrial catheter for venous access in leukaemic patients.

A large-diameter indwelling subcutaneous right-atrial catheter was inserted in 25 patients with haematological malignancies and neutropenia to provide ready access to the venous system for all infusions and blood aspirations. The median duration of catheter placement was 70 days. In 23 patients (92%) the catheter was used successfully until remission or death. Catheter-related exit-site infectons, generally mild, occurred in 14 patients (56%), Staphylococcus epidermidis being the predominant organism cultured. Septicaemia occurred in 11 neutropenic patients (44%). In 2 patients the same organism was grown from blood and exit site. The use of this catheter greatly facilitates patient care and support, minimises discomfort, and is associated with an acceptable rate of complications.

Acute Disease↗