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Biomedical subjects

J F Toole

Publications and source records attributed to J F Toole.

At least 127 records · Page 7Linked to original sources
PubMed1975

Transient ischemic attacks due to atherosclerosis. A prospective study of 160 patients.

Patients with transient ischemic attacks (TIAs) due to atherosclerosis were studied by aortocranial arteriography. Onset of TIAs was before age 55 in 24% and between 55 and 64 in 47%. Men exceeded women by two to one. Of 160 patients, 77 were treated medically and 82 surgically. Five died in the immediate postoperative period. In the survivors, mortality has been the same in the medically and surgically managed groups. For patients with multiple lesions, surgical reconstruction of the carotid arteries was associated with very high surgical risk. In the medically treated group, anticoagulant therapy reduced the frequency of TIAs, but did not appear to protect patients from stroke. Mortality was 23% at four years, 57% of deaths being attributable to myocardial infarction and 38% to stroke.

Adult↗
PubMed1975

The steal syndromes.

Blood can be stolen from almost any vascular bed and redistributed. The external carotid artery can steal from cerebral structures when occlusion of the common carotid artery proximal to the bifurcation causes reversal of flow through the internal carotid artery (13, 45, 46). The external carotid artery has also been shown to steal blood flow from the vertebral artery distribution (13, 74). Double steals involving both the subclavian and external carotid arteries are seen in 1 to 2% of patients (13, 46). There is also the "triple steal syndrome" wherein both subclavian arteries and one external carotid artery are involved (14).

Angiography↗
PubMed1973

Informed consent.

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Disclosure↗