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Biomedical subjects

J F Stoltz

Publications and source records attributed to J F Stoltz.

At least 217 records · Page 12Linked to original sources
PubMed1977

[X-ray diffraction of the collagen contained in blood vessels].

An X-ray diffraction study has been undertaken on Human and Rabbit blood-vessels. Vessels are stretched 500% and the diagrams present a great analogy with those obtained from collagen. Thus, it appears, that it is possible to determine by X-Rays some pathological anomalies of the collagen in vessels.

Animals↗
PubMed1977

[Evaluation of a method of study of platelet aggregates using formol fixation].

A new approach for testing platelet aggregates by formol fixation (Wu and Hoak) is presented. The investigations are made either in vitro by the study of aggregation in the presence of ADP, or in vivo after thrombin ADP perfusion in the rabbit. The calculation of an index of aggregability comparing fixed and non fixed platelets permits an evaluation of the presence of aggregates.

Adenosine Diphosphate↗
PubMed1977

Study of carboxyl groups on the human blood platelet membrane.

The authors have studied the whole carboxyl groups of the platelet membrane using liquid phase electrophoresis and an initial step of activation of the acid group by a water soluble carbodiimide (ethyl-l-diméthyl-aminopropyl-3-carbodiimide), followed by the action of a nucleophilic molecule. The calculation based on the theory of Gouy-Chapman have shown the existence of 24, 7.10(5) groups per cell. That is a number about 2.5 fold superior to the carboxyl groups of sialic acid as determined by the action of neuraminidase.

Blood Platelets↗
PubMed1976

[Significance of photometric demonstration of variations in platelet form during aggregation caused by ADP: reality or artefact].

After a short theoretical recall concerning the problem of light scattering, the author presents some experimental studies about the variations of light intensity scattered by platelets during ADP induced aggregation. In contrast to the reports by Born and Michal, experimental demonstration is given, showing that these variations cannot be interpreted in term of shape change, as no theoretical basis supports these phenomea.

Adenosine Diphosphate↗
PubMed1976

Study of antigenic varieties of group A red cells, platelets and lymphocytes using liquid phase electrophoresis.

The authors attempt to study the presence of subgroups of the phenotype A on lymphocytes and platelets with the help of liquid phase electrophoresis. The results show that anti-A of B serum reduces the electrophoretic mobility of red cells, platelets and lymphocytes of group A but leaves unchanged the mobility of group O or B cells. The same variations are observed in red cell lymphocytes and platelets. The authors suppose that the distribution of antigenic sites is identical in these elements.

ABO Blood-Group System↗
PubMed1976

[Evaluation of a method of study of platelet aggregates by formol fixation].

An approach for testing platelet aggregates by formol fixation is presented. The investigations are made either in vitro by the study of aggregation in the presence of ADP, or in vivo after thrombin perfusion in the rabbit. The calculation of an 'index of aggregability' comparing fixed and non-fixed platelets permits an evaluation of the presence of aggregates.

Adenosine Diphosphate↗
PubMed1975

[Study of the osmotic behaviour of human platelets].

Observation of the behaviour of platelets in hypotonic media affords an approach to the evaluation of their fragility. It should be possible to apply such a test to various fields such as the study of rheological properties of platelets, the investigation of certain pathological cases and eventual alterations during storage. The curve obtained reflects a continuous distribution of platelet osmotic fragility.

Blood Platelets↗
PubMed1975

[Platelet aggregation induced by ADP: a light scattering study].

The absorption and the ADP-induced platelet aggregation have been studied by the technique of light scattering. The results show, that the platelets have no specific absorption and that the aggregation test measures predominantly the diminution of free platelets. The determination of platelet kinetics and shape changes is not specific.

Adenosine Diphosphate↗
PubMed1975

In vitro and in vivo influence of penicillin G on platelet aggregation.

The influence of penicillin G on the in vitro and in vivo ADP-induced platelet aggregation and on the platelet electrophoretic mobility has been studied. The in vitro investigations in presence of penicillin concentrations varying between 1,000 and 10,000 IU/ml of plasma, and doses of adenosine diphosphate (ADP) between 0.3 and 25/muM/ml, have shown that the photometric aggregation, as well as the screen filtration pressure are both decreased, according to the doses of antibiotic and ADP. The electrophoretic mobility is also impaired. The in vivo study of 8 patients submitted to massive penicillin therapy for bacterial endocarditis seems to be in agreement with the in vitro results, and has shown a prolonged bleeding time, an hypoadhesiveness, an impaired photometric aggregation with an early disa-gregation and a decrease of the screen filtration pressure and platelet electrophoretic mobility.

Adenosine Diphosphate↗