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Biomedical subjects

J F Reinisch

Publications and source records attributed to J F Reinisch.

31 records · Page 2Linked to original sources

The effects of streptokinase on ischemic flaps.

Prolonged ischemic periods may inhibit success in microsurgical procedures. Impairment of fibrinolytic activity could be a factor contributing to this problem. Ischemic epigastric flaps in the rat were used as a model to measure the potential of streptokinase to improve blood flow and tissue survival. A moderate but statistically significant improvement in flap survival was observed and is felt to be due to the enhancement of fibrinolytic activity previously impaired by ischemia. Saline irrigation alone in control animals was found to be detrimental to flap survival. Streptokinase might prove beneficial when dealing with an ischemic replant or free flap.

Animals↗

Sleep apnea in mandibular hypoplasia.

Obstructive sleep apnea is an insidious and potentially life-threatening disorder that is probably more prevalent than has been previously diagnosed. Since there is generally some mechanism for relief of the respiratory obstruction, this is a very successfully treatable disorder. A strong index of suspicion should be held in cases of oronasal or pharyngeal abnormalities with a potential for respiratory obstruction. Loud snoring (particularly a recent change) and daytime hypersomnolence should alert us. In-hospital sleep monitoring and arterial gas measurements can provide a definitive diagnosis.

Abnormalities, Multiple↗

The transnasal--transsphenoidal approach for pituitary surgery.

The transnasal-transsphenoidal approach for pituitary surgery is an effective procedure that benefits nicely from a team concept utilizing the expertise of both the neurosurgeon and the plastic surgeon. Experience with eleven cases is presented along with a review of historical information and a description of the surgical technique.

Acromegaly↗

Late correction of orbicularis discontinuity in bilateral cleft lip deformity.

The absence of muscle in the prolabial segment and the failure to identify and join the fibers of the orbicularis muscle from the lateral lip segments at the time of initial lip repair frequently result in a characteristic bulge above the vermilion laterally. This bulge is caused by the bunching of the orbicularis oris as the result of its discontinuity in the prolabial segment. Late repair of this deformity is possible. In a series of fifteen patients with previously repaired bilateral cleft lips, lateral mobilization and midline suturing of the separated segments of the orbicularis oris muscle have been employed to correct the orbicularis bulge. Significant improvement in oral animation and in facial aesthetics have been noted in these patients.

Adolescent↗