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Biomedical subjects

J F Reidy

Publications and source records attributed to J F Reidy.

At least 91 records · Page 5Linked to original sources

Comparative trial of iohexol 350, a non-ionic contrast medium, with diatrizoate (Urografin 370) in left ventriculography and coronary arteriography.

In a prospective double blind randomised study in 25 consecutive patients a conventional ionic contrast medium (Urografin 370) was compared with the new non-ionic medium iohexol 350 ( Omnipaque ) in left ventriculography and coronary arteriography. In left ventriculography there was a clear patient preference for iohexol by both a visual analogue scale and independent observer assessment. Iohexol also induced a smaller increase in heart rate or decrease in systolic blood pressure than Urografin. In coronary arteriography iohexol resulted in a smaller reduction in heart rate and systolic blood pressure, a smaller maximum increase in RR interval, less prolongation of the PQ and QT intervals and QRS duration, and a lower incidence of induced chest pain, ST segment depression, or T wave deflection.

Adult↗

Femoral artery flow and pain during lumbar aortography: comparison of ionic and non-ionic contrast media.

A method is described for non-invasively measuring the increase in lower limb blood flow during transfemoral lumbar aortography. Flow measurements were made using a continuous wave Doppler-shift ultrasound transducer placed over the contralateral femoral artery. The effect of the non-ionic contrast medium B15000 (Iopamidol), conventional contrast medium (Urografin 370) and Urografin 370 plus Lignocaine were compared in a double-blind trial. All three produced an increase in flow which reached a peak between 12 and 45 s after injection. The peak flow following Iopamidol was significantly lower than that from both Urografin 370 alone and with addition of Lignocaine. There was a difference of lesser degree between Urografin 370 plus Lignocaine and Urografin 370 alone; however, this was not statistically significant. The subjective assessments of pain and patient 'discomfort' paralleled these objective flow measurements.

Aged↗

Transcatheter occlusion of coronary to bronchial anastomosis by detachable balloon combined with coronary angioplasty at same procedure.

The first case of non-operative occlusion of a large coronary to bronchial anastomosis is described. The patient who had severe angina had also a critical stenosis of the anterior descending coronary artery which was successfully dilated by an angioplasty procedure. An occluding balloon was detached in the large distal circumflex coronary artery, beyond all the normal branches. At a repeat catheterisation study seven months later the balloon was intact and in position, and the anastomosis remained occluded.

Aged↗

Transcatheter occlusion of a Blalock-Taussig shunt with a detachable balloon in a child.

A case of transcatheter occlusion of a Blalock-Taussig shunt with a detachable silicone filled balloon is described. This 11 year old boy had previously had a repair of tetralogy of Fallot together with ligation of a large Blalock-Taussig shunt. Though there was a good surgical result, the shunt proved to be incompletely closed leaving a significant left to right shunt. As an alternative to a further operation a silicone filled balloon was detached in the Blalock-Taussig shunt and this successfully closed the fistula.

Angioplasty, Balloon↗

Successful late non-surgical removal of intracardiac catheter fragment.

A patient was discovered to have a retained intracardiac catheter fragment more than two years after successful aortic valve replacement. During this time the patient had had extensive investigations and several hospital admissions for suspected subacute bacterial endocarditis, as well as for episodes of supraventricular tachycardia. The catheter fragment was successfully removed via a percutaneous catheter approach despite the very long interval that had elapsed since its detachment.

Cardiac Catheterization↗

Embolization of a coronary fistula with a controlled delivery platinum coil in a 2-year-old.

Congenital coronary artery disorders are rare. Elective closure is proposed in view of the morbidity reported later in life. Excellent results have been reported with surgery, and recently catheter occlusions have been successful. We report the case of a 2-year-old girl whose coronary artery fistula was occluded with a special controlled delivery coil system.

Cardiac Catheterization↗

Interlocking detachable platinum coils, a controlled embolization device: early clinical experience.

PURPOSE: To present the early clinical experience of a new mechanically controlled-release embolization device--the interlocking detachable coil (IDC)--in complex embolization outside the head. METHODS: IDCs were used only when conventional embolization techniques were considered too risky or unsafe. The coils consist of unfibered coiled platinum (0.012 inch), mechanically connected to a pusher wire and deployed through a Tracker 18 catheter. IDCs come in a range of diameters (2-8 mm) and lengths (1-30 cm). RESULTS: A total of 87 IDCs were used for 27 procedures in 25 patients (mean 14.5 years) to occlude 31 arteries or vascular lesions. Control of the coil and its release were satisfactory and all coils ere fully retrievable up to the point of deployment. Two IDC coils embolized inadvertently but were retrieved; there were no other complications. The IDC coils could not be satisfactorily placed one high-flow arteriovenous (AV) fistula, and in another case there was a small residual fistula. Occlusion was produced in 29 of 31 lesions. Ancillary techniques were needed in 5 patients: temporary balloon occlusion in 2 and 0.038-inch coils in 3. CONCLUSION: The IDC coil is an effective device that allows controlled embolization to be performed, especially in aneurysms and in high-flow AV fistulas in children.

Adolescent↗

Gianturco self-expanding stents: clinical experience in the vena cava and large veins.

Twenty-five patients with stenosis of the vena cava (21) and other large veins (4) have been treated with self-expanding Gianturco metallic stents. Eighteen patients had superior vena cava syndrome. In 17, the stricture was due to malignant superior vena cava compression recurrent after maximum tolerance radiotherapy and/or chemotherapy. In 16 of these patients there was early symptomatic relief. In 1 patient with a benign posttraumatic superior vena cava stricture, the stenosis was not relieved, and occlusion occurred after 1 month. Stenoses associated with dialysis shunts were relieved in 2 other patients. Two malignant and one benign inferior vena cava stenoses were relieved either until death, or in the benign case, for 30 months. One malignant subclavian vein obstruction occluded after 24 h due to stent misplacement and another with extrinsic mediastinal compression remained patent until death, extensive thrombus having been lysed prior to stent placement. The results of this short series suggest that the Gianturco self-expanding stent in the vena cava and large veins is easy and safe to place, and in most cases produces almost immediate palliation of the distressing effects of venous obstruction, often in a preterminal and inoperable patient.

Constriction, Pathologic↗

Use of through-and-through guidewire for delivering large stent-grafts into the distal aortic arch.

The availability of large diameter stent-grafts is now allowing the endovascular treatment of thoracic aortic aneurysms. Most aneurysms are closely related to the distal arch and it is thus necessary to pass the delivery systems into the arch to effectively cover the proximal neck. Even with extra-stiff guidewires in position, it may still be difficult to achieve this, as a result of tortuosity at the iliac arteries and the aorta. We detail a technique where a stiff guidewire is passed from a brachial entry point through the aorta and out at the femoral arteriotomy site. This allows extra-support and may enable the delivery system to be passed further into the aortic arch than it could with just the regular guidewire position.

Accidents, Traffic↗

Arteriovenous fistula at the site of balloon dilatation complicating femoropopliteal angioplasty.

We describe an arteriovenous fistula (AVF) at the site of balloon dilatation immediately after percutaneous transluminal angioplasty (PTA) of the femoropopliteal artery. This occurred during an otherwise uncomplicated angioplasty with a good clinical result. The AVF closed spontaneously within 2 months as monitored by color duplex ultrasound. This uncommon complication of PTA is not widely recognized.

Aged↗

Successful repeat transcatheter ablation of a mediastinal parathyroid adenoma 6 years after alcohol embolization.

Recurrent hyperparathyroidism is rare following transcatheter ablation of mediastinal parathyroid adenomas. When it occurs it is usually early and resistant to further attempts at ablation. We present a patient with primary hyperparathyroidism in whom two surgical attempts at cure had been unsuccessful. Subsequently, a mediastinal adenoma was demonstrated angiographically and embolized with absolute alcohol. Hyperparathyroidism recurred 6 years later and the mediastinal adenoma was subsequently successfully ablated a second time by angiographic embolization with ionic contrast medium.

Adenoma↗

Successful intraarterial thrombolysis of an ischemic limb four days after laparoscopic cholecystectomy.

Intraarterial thrombolysis is usually contraindicated after abdominal surgery because of the risk of bleeding. However, it is a highly effective treatment for embolic acute limb ischemia, particularly for clearing the distal vessels. We report a case in which intraarterial thrombolysis was safely used 4 days after laparoscopic cholecystectomy in a patient with an acutely ischemic leg due to embolus.

Acute Disease↗

Short-term femoral nerve complications following percutaneous transfemoral procedures.

PURPOSE: To determine the prevalence of transient femoral nerve anesthesia following transfemoral angiographic procedures. PATIENTS AND METHODS: Fifty-eight patients undergoing a variety of routine transfemoral procedures underwent a neurologic assessment within an hour of the procedure. RESULTS: Nine patients (16%) were found to have complete or partial deficits in the ipsilateral femoral nerve territory. All deficits were transient. CONCLUSIONS: Transient femoral nerve deficits are not uncommon following transfemoral procedures. With the advent of true outpatient vascular procedures (where the patient may walk away after only a 30-minutes recovery period following a transvenous intervention or after 60 minutes following arteriography), transient neurologic problems related to the infiltration of local anesthetic around the femoral artery assume real clinical importance.

Adult↗