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Biomedical subjects

J F Potter

Publications and source records attributed to J F Potter.

At least 145 records · Page 8Linked to original sources
PubMed1983

Breast cancer in blacks, Asians and whites in Birmingham.

A retrospective study was mounted into the frequency of breast cancer in blacks, whites and Asians attending Dudley Road Hospital in the years 1970-1981 inclusive. This figure was compared with the ethnic distribution of the surrounding population and of admissions for all causes. Breast cancer was uncommon in both ethnic minorities compared with whites, but was commoner in blacks than in Asians. These trends are similar to the World Health Organization figures for Britain, Jamaica and India. Differences in parity and breast feeding do not explain the variability of breast cancer in this study.

Adult↗
PubMed1983

Blood pressure and pressor mechanisms during alcohol withdrawal.

Blood pressure, alcohol withdrawal symptoms and plasma levels of cortisol, aldosterone and renin activity and serum dopamine beta-hydroxylase concentrations were measured in 65 alcoholics on the first and fourth days after admission for detoxification. On the day after admission blood pressure was elevated (greater than 140/90 mmHg) in 32 patients (49%) and was 160/95 mmHg or more in 21 (32%). Plasma renin activity was elevated in 41 patients and plasma aldosterone concentration in 14, but neither correlated with blood pressure. Plasma cortisol levels were elevated in 13 patients and were positively correlated with systolic blood pressure. Blood pressure and all biochemical measures fell significantly by the fourth day while urine volume and sodium output, low on admission, increased significantly. Urinary metanephrine levels were elevated in four of 31 patients in whom they were measured on admission. Alcohol withdrawal was accompanied by raised blood pressure and high plasma concentrations of cortisol, renin and aldosterone but only plasma cortisol concentrations and withdrawal symptoms were significantly related to blood pressure.

Alcoholism↗
PubMed1983

Primary parotid cancer: factors influencing recurrence.

Recurrent disease was evaluated in 82 patients with primary parotid cancer as a function of multiple parameters including cell type, stage of disease, and extent of surgery. Stage III disease had the highest rate of recurrence (89%). Recurrence in Stage III disease appeared independent of extent of primary surgical management. The poor prognosis, 12 per cent survival at five years, associated with recurrence suggests adjuvant modalities should be utilized in the initial treatment of Stage III disease. In Stage I disease, the extent of surgery becomes more critical. In patients with Stage I disease and low-grade malignancies, superficial parotidectomy is an acceptable method of treatment. This is valid provided surgical margins are free of disease. However, patients with high-grade malignancies and Stage I disease undergoing superficial parotidectomy have a high rate of recurrence, 45 per cent of our cases. The results suggest that more extensive surgery and/or adjuvant radiation should be utilized in this subgroup of patients.

Adolescent↗
PubMed1982

Effect of aging on the cardiothoracic ratio of men.

The potential usefulness of chest radiographs in the assessment of physical dimensions was examined in 243 men (age range 20-95 years) who had been followed up for an average of 12.3 years. From 1,124 of these films, measurements of cardiac diameter (CD) and thoracic diameter (TD) were made, and the cardiothoracic ratio (CTR) was calculated. Cross-sectional age differences were associated with a tendency toward increases in the CD and CTR throughout the lifespans of the 243 men, regardless of the presence or absence of heart disease. The thoracic diameter (TD) was greater in middle-aged than in young subjects, but less in the oldest than in the middle-aged subjects. Cumulative percentage curves for the CTR showed a shift to higher fiftieth to ninetieth percentile values with age. However, among the subjects free of heart disease, only one (age 95) had a CTR exceeding 50 per cent. Longitudinal analysis data agreed with the cross-sectional data. Forty-nine deceased subjects were matched with living subjects of the same heart disease classifications. Increases in the CD and CTR were predictive of death in the group with heart disease but not in the group without identifiable heart disease. An increase in CD was not correlated with an increase in systolic blood pressure. The decline in TD appeared to reflect a decline in rib-cage mobility with aging.

Adult↗
PubMed1975

The modified Tokyo larynx: an improved pneumatic speech aid.

The Tokyo, or Japanese, artificial larynx is a pneumatic speech aid with superior sound production used in the rehabilitation of laryngectomized patients. Although there are some difficulties with its use, modifications have been developed that eliminate the major problems. Three brief case reports demonstrate the effectiveness of this speech aid when properly prescribed.

Aged↗
PubMed1975

Preoperative irradiation and surgery for certain cancers.

Failure to cure cancer by surgery is caused by inability to remove all local extensions of the lesion or from prior or synchronous dissemination of tumor cells. Laboratory evidence has suggested that preoperative irradiation of the primary tumor can increase cure rates. In the clinical realm, the efficacy of preoperative irradiation appears to vary with specific tumors. Lung cancer shows no improvement in survival. Cancers of the bladder and breast may show enhancement of cure rate. Data indicate that cancer of the rectosigmoid does benefit from preoperative therapy. Adherence to important factors of dosage and timing of operation is necessary to prevent undesirable complications. Randomized clinical trials are needed to establish the efficacy of this combined modality treatment system. This is particularly true since both these modalities can be applied on a wide-scale basis if beneficial effects are conclusively demonstrated.

Breast Neoplasms↗