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Biomedical subjects

J F Peters

Publications and source records attributed to J F Peters.

35 records · Page 2Linked to original sources
PubMed1975

Electrical phenomena associated with movements of the eyelid.

A series of observations were made on a normal subject, a subject with a non-metallic prosthesis and one with unilateral facial paralysis in order to demonstrate the role of the eyelid in the production of the electrical potential seen during blinking. The findings support the hypothesis that moving the eyelid over the positively charged cornea of an intact ocular globe alters the electrical field around the globe and is therefore responsible for the recorded potentials. The data are consistent with previous findings that the polarity of the potential due to eyelid movement is opposite that due to vertical ocular rotation in the same direction. The potential occurs in the absence of ocular rotation.

Adult↗
PubMedDate not supplied

Strategy for molecular cloning of the fragile X site DNA.

Fragile X syndrome is a common form of mental retardation associated with a fragile site on the human X chromosome. We have recently demonstrated that the fragile X chromosome, when isolated within a somatic cell hybrid, often participates in translocations involving rodent chromosome arms. Cytogenetic and molecular evidence strongly suggests that the human breakpoint of these translocations is within the fragile X sequence. Hence, the joining of heterologous DNA (i.e. from two species) may permit the molecular cloning of the fragile X site. We describe here the cloning approach employed to enhance the isolation of interspecific chromosome translocation junctions. The human portion of the translocation junction should be derived from the fragile X site sequence.

Animals↗
PubMedDate not supplied

Quantifiable hearing and no ABR: paradox or error?

Reports concerning the inability to record at least wave V of the ABR in patients with quantifiable hearing have generally been confined to patients with demonstrable neurological diseases. Four patients with no neurological evidence of brainstem dysfunction in whom the ABR's were either absent or showed thresholds inappropriate for the audiometric configurations are presented.

Adult↗