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Biomedical subjects

J F Pagel

Publications and source records attributed to J F Pagel.

3 recordsLinked to original sources

Nightmares.

Although sporadic nightmares may be normal responses to stress, chronic nightmares can be troublesome. Nightmare syndrome involves dreams during REM sleep and is associated with abnormal psychologic tests and psychiatric disorders. Night terrors are most common in childhood, occur during deep sleep and rarely reflect underlying pathology. Post-traumatic stress disorder produces recurrent and repetitive nightmares. The onset of nightmares in an adult is often associated with medication or illness.

Adolescent

Diagnosis and treatment of insomnia.

Insomnia is a disorder of initiation and maintenance of sleep that results in daytime somnolence. The differential diagnosis of the various forms of insomnia is based primarily on the history, including information from the sleeping partner. The possibility of underlying depression or sleep apnea must be given consideration in every patient with insomnia, because inappropriate therapy may be dangerous in these instances. In general, the benzodiazepines have supplanted the traditional hypnotics in the treatment of insomnia.

Anti-Anxiety Agents

Sleep disorders and insomnia.

Primary sleep disorders include narcolepsy, the Pickwickian syndrome, sleep apnea in infants and other rare conditions. Secondary sleep disorders occur in depression, alcoholism, endocrinopathies, heart failure and pregnancy. Medical symptomatology often increases during rapid-eye-movement (REM) sleep, when physiologic activity is high. Insomnia, the most common sleep disorder, requires careful work-up, attempts at environmental manipulation and judicious short-term pharmacotherapy. Pharmacologic manipulation of sleep is beset with complications. A basic understanding of properties and side effects of the sleep-inducing drugs is needed in order to select the optimal agent.

Humans