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J F Meder

Publications and source records attributed to J F Meder.

118 records · Page 7Linked to original sources

[Radioanatomy of cerebral arteriovenous malformations].

New imaging modalities permit detailed knowledge of the anatomy of cerebral arteriovenous malformations. Magnetic resonance imaging (MRI) provides morphological data, size and topography of the nidus, anatomic relationship, as well as dynamic information particularly with the use of MR angiography. Selective and hyperselective cerebral angiography provide information about the angioarchitecture and search for associated vascular abnormalities such as aneurysms. It is therefore possible to distinguish malformations associated with a high risk of hemorrhage and to define the indications for radiosurgery.

Cerebral Angiography↗

Dysgenesis of the internal carotid artery associated with transsphenoidal encephalocele: a neural crest syndrome?

We describe two original cases of internal carotid artery dysgenesis associated with a malformative spectrum, which includes transsphenoidal encephalocele, optic nerve coloboma, hypopituitarism, and hypertelorism. Cephalic neural crest cells migrate to various regions in the head and neck where they contribute to the development of structures as diverse as the anterior skull base, the walls of the craniofacial arteries, the forebrain, and the face. Data suggest that the link between these rare malformations is abnormal neural crest development.

Adult↗

Dural arteriovenous fistulas of the posterior fossa draining into subarachnoid veins.

PURPOSE: To describe the clinical presentation, angioarchitecture, and risks and problems of therapy in patients with dural arteriovenous malformations of the posterior fossa draining into subarachnoid veins. PATIENTS AND METHODS: Twelve patients with dural arteriovenous malformations of the posterior fossa draining into subarachnoid veins were studied. RESULTS: These fistulas often presented with intracranial hemorrhage (eight cases) and myelopathy (two cases). They were located in the tentorium (six cases) or at the skull base (six cases). The arterial supply was provided by branches of the external carotid artery (nine cases), by the posterior meningeal branch of the vertebral artery (nine cases), and by the meningohypophyseal trunk (three cases). The fistulas drained directly into a cortical vein (six cases) or into a venous lake (six cases). In two cases, perimedullary draining veins were observed. The treatment modalities were endovascular embolization alone (two cases), surgery alone (five cases), and embolization followed by surgery (three cases). Despite the treatment, four patients died; in two cases, intracranial hemorrhage recurred. CONCLUSIONS: Subtotal occlusion of a fistula by surgery or embolization alone is not protective against further complications, especially hemorrhage. The goal of treatment is to achieve a rapid and complete anatomical cure; combined endovascular and neurosurgical treatment seems to be the therapeutic choice.

Adult↗

Spontaneous disappearance of a spinal dural arteriovenous fistula.

A case of proved regression of an asymptomatic dural arteriovenous fistula is reported. At the time of diagnosis, myelography showed dilated perimedullary veins. Angiography demonstrated a radicular outflow from these veins to the epidural plexus. A follow-up angiogram 5 years later was normal.

Angiography↗

[Isolated dissection of the posterior cerebral artery].

Two cases of isolated dissection of the posterior cerebral artery responsible for ischemic stroke are reported. Nine probable or certain additional cases were found in the literature. Most patients were female. The clinical presentation consisted of ischemic symptoms in 6 patients, subarachnoid hemorrhage in 4, and both symptoms in 1. Headache was present in almost all patients. The most prevalent angiographic picture was an eccentric stenosis followed by fusiform dilatation of the P1-P2 segments of the posterior cerebral artery. A double-lumen sign was observed in 3 cases. A favorable outcome was usual in cases with ischemic symptoms. Potential benefits from anticoagulants (in case of ischemic symptoms) or surgery (in case of subarachnoid hemorrhage) are unknown.

Adult↗