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Biomedical subjects

J F Magrina

Publications and source records attributed to J F Magrina.

52 records · Page 3Linked to original sources
PubMed1982

Management of condylomata acuminata with the carbon dioxide laser.

Ninety-four patients with condylomata acuminata of the lower genital tract and perianal region were treated with the carbon dioxide laser. Most were managed in the outpatient clinic, but 1 to 4 treatments were required depending upon extent of involvement. Of 90 patients, 75 (83.3%) were free of lesions on all follow-up examinations after initial treatment. Of 15 patients with recurrent lesions, 13 underwent a second laser treatment; 7 of these 13 have been subsequently free of condylomata. The overall success rate was 91%. The carbon dioxide laser provides an appealing method of management of condylomata acuminata because of its precision, rapid healing without scarring, and safety when used during pregnancy.

Adolescent↗
PubMed1981

The carbon dioxide laser in cervical intraepithelial neoplasia: a five-year experience in treating 230 patients.

Two hundred and thirty patients with cervical intraepithelial neoplasia were treated over a 5-year period with the carbon dioxide laser at the University of Kansas. Analysis of cytologic findings, biopsy results, location of the lesion, treatment factors, and recurrence rates are reported. Ninety percent of the patients were cytologically free of intraepithelial neoplasia at the end of the study.

Carbon Dioxide↗
PubMed1980

Pelvic "lipolymph nodes": a consideration in the differential diagnosis of pelvic masses.

Twelve patients with pelvic "lipolymph nodes" were seen at the Mayo Clinic during a period of 26 years. Most of the patients were perimenopausal or postmenopausal, and all but one were obese. The average size of the nodes was 6.6 cm, with the range being 2 to 14 cm. The most frequently involved nodes were the external iliac and obturator groups. Excretory urography and pelvic ultrasound scan (high-resolution scanner) were helpful in determining the extraperitoneal location and the solid nature of the tumors. Lymphangiography performed in one case was helpful in confirming the nodal origin of the pelvic tumor. Exploratory laparotomy was required to determine the exact nature of the lesion in all patients. The treatment consisted of simple removal of the involved nodes. No recurrences have been observed.

Adipose Tissue↗
PubMed1979

Stage I squamous cell cancer of the vulva.

A review of 106 patients with Stage I squamous cell cancer of the vulva treated at the Mayo Clinic from 1950 through 1975 is presented. Microinvasive lesions (5 mm penetration or less) were present in 96 patients (91%); invasive lesions (more than 5 mm penetration) were diagnosed in 10 (9%). Inguinal node involvement was present in nine patients (8.4%); one of these also had pelvic node involvement. Recurrence developed in 13 patients (12%). Four patients experienced inguinal node metastasis after initial surgical therapy. The incidence of positive nodes among patients with lesions invading the stroma for 3 mm or less was 3%. Thus, individualization for inguinal lymphadenectomy may be possible according to the age and condition of the patient when the depth of invasion is 3 mm or less.

Adult↗
PubMed1979

Intentional ureteral ligation in advanced pelvic malignant disease.

It is now widely accepted that debulking operative resections can provide effective palliation for some patients with advanced pelvic malignancy, particularly with those malignancies originating in the ovary. Some of these radical operations require the resection of long segments of the ureter and portions of the bladder. Although there is a variety of techniques that can be used in this situation to restore the continuity of the urinary tract, in some instances a simple ureteral ligation may represent the best method of managing the "short ureter." In our experience with 23 patients who underwent intentional ureteral ligation, the procedure was found to be safe, expeditious, and beneficial in managing some of the complex problems associated with advanced pelvic malignant disease.

Adult↗
PubMedDate not supplied

Mucinous adenocarcinoma in an ovarian remnant.

The ovarian remnant syndrome, a complication of bilateral salpingo-oophorectomy, is progressively receiving more attention in the gynecological surgery literature. The syndrome is manifested by pelvic pain and a palpable or sonographic finding of a pelvic mass. However, in rare cases, patients can present with large masses and radiographic suggestion of malignancy. We present the case of a 76-year-old white female, 23 months after bilateral salpino-oophorectomy at the same institution, complaining of 3.5 months of right flank and abdominal pain. Clinical and radiological evidence of a right ovarian remnant was discovered. Subsequent laparoscopic resection was consistent with a well-encapsulated mucinous adenocarcinoma in a right ovarian remnant. Curiously, this patient had no history of endometriosis, dense pelvic adhesions, pelvic inflammatory disease, or difficulty encountered during the original hysterectomy. This is the seventh published case report in the international literature about carcinoma developing in an ovarian remnant. However, this case differs in that the patient had no preexisting gynecologic conditions at the time of hysterectomy and bilateral salpingo-oophorectomy to account for residual ovarian tissue. Additionally, the oophorectomy was performed vaginally, in contrast to multiple previous case reports.

Adenocarcinoma, Mucinous↗