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Biomedical subjects

J F Lehrer

Publications and source records attributed to J F Lehrer.

28 records · Page 2Linked to original sources

Perilymphatic fistula--a definitive and curable cause of vertigo following head trauma.

Vertigo or disequilibrium occurring in patients after concussive and nonconcussive head trauma may be due to a pathologic perilymphatic fistula from the inner ear through the oval and round window areas of the middle ear. Of 33 patients who had successful grafting of the fistulous area at middle ear exploration, 32 had resolution of vertigo, and 12 of 23 who had an associated hearing loss had improved hearing. Perilymphatic fistulas associated with vertigo and hearing loss after head trauma can be diagnosed with great certainty and are surgically curable in the great majority of cases. Patients with post-concussive syndrome, whose symptoms include vertigo or disequilibrium, should have a thorough otologic evaluation for the possibility of a perilymphatic fistula.

Craniocerebral Trauma↗

Abnormalities of the stapedius reflex in patients with vertigo.

Analysis of the latency, amplitude, and rise characteristics of the stapedius reflex as demonstrated on a strip recorder revealed abnormalities in patients with vestibular neuronitis and other vertigo syndromes. The findings in vestibular neuronitis, acute labyrinthitis, perilymphatic fistulas, Meniere's disease, cerebrovascular insufficiency, and metabolic vertigo are described. Alterations in the stapedius reflex included increase in latency, decrease in amplitude, stepping of the rise, and absence of the reflex. This study suggests that absence of the reflex can be associated with vertigo as well as with acoustic neuromas and other retrocochlear lesions. The findings of abnormalities in vestibular neuronitis support a brain-stem localization as the site of lesion in this disease.

Cerebrovascular Disorders↗

Use of the glycerin test in the diagnosis of post-traumatic perilymphatic fistulas.

A new application of the glycerin test in the diagnosis of post-traumatic perilymphatic fistulas is described. Temporary disappearance of abnormal responses to the fistula and Quix tests and improvement in the hearing occurred. The glycerin test was useful in confirming the diagnosis of post-traumatic perilymphatic fistula in 13 patients in whom fistulas were found at middle ear exploration.

Adolescent↗

Onset and duration of positive responses to the glycerin test in patients with Menière's disease.

The onset and duration of positive responses to the glycerin test were studied in 28 patients with Menière's disease who had positive responses to the test. The responses were measured for three hours at 30-minute intervals after the ingestion of glycerin. Positive responses were found as early as 30 minutes after ingestion of glycerin. The responses had often become negative by two to three hours. Testing of patients with Menière's disease only at the end of a three-hour interval after ingestion of glycerin will produce a large proportion of false-negative responses, as evidenced by a 39 per cent negative response rate three hours after ingestion of glycerin.

Glycerol↗