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Biomedical subjects

J F Knapp

Publications and source records attributed to J F Knapp.

50 records · Page 3Linked to original sources

Pediatric gunshot wounds--powder and nonpowder weapons.

A retrospective chart review of 102 consecutive cases of gunshot wound injuries in children was conducted. Victims were identified by emergency department log review and computer search for inpatient discharge diagnoses. Results are compared with other studies. Nonpowder weapons are found to be involved in a preponderance of cases. In 66% of the cases in which the weapon was known, a nonpowder weapon was used. Length of hospital stay, operations performed, and outcome were compared for the handgun and nonpowder weapon groups. Nonpowder weapons were found to have inflicted major injury in as many patients as did handguns. Methodologic problems of studying gunshot wounds in children are discussed. It is suggested that injury prevention strategies address nonpowder weapons as well as handguns.

Adolescent↗

Scalp colonization by Trichophyton tonsurans in an urban pediatric clinic. ?Asymptomatic carrier state.

Random culturing of the scalp in 200 healthy children in a large metropolitan children's hospital revealed that eight (4%) of the patients had cultures that were positive for Trichophyton tonsurans variety sulfureum. Infections were not clinically apparent and were asymptomatic. All of the patients with positive cultures were black and six braided their hair. Trichophyton tonsurans appears to exist in an asymptomatic state in this well-defined population of children.

Black People↗

Unusual mechanism of Chance fracture in an adolescent.

Transverse fractures of the vertebral arch or Chance fractures are rare in children. The few cases described have been associated with lap-type seat belt use. The adolescent female reported sustained a transverse fracture of L2 from a fall. This is an unusual mechanism of injury producing a Chance-type fracture in an adolescent.

Accidental Falls↗

Injuries associated with downhill sledding.

During the winter season of 1985 to 1986, 30 children presented to the emergency department with injuries related to downhill sledding. All of the patients were seen and treated during December 1985, which was an unusually cold and snowy month. The age range of the patients was six to 16 years. Six patients required admission, and all were related to head and/or abdominal trauma. The special characteristics of the sled, the environment, and the rider work in concert to produce injuries. The injury is most likely to occur under cold, icy conditions. After analysis of this series of patients, it is concluded that downhill sledding injuries can be minimized. The factors that make this activity dangerous are defined, and safety precautions are suggested.

Adolescent↗

Ventricular septal defect following blunt chest trauma in childhood: a case report.

We report a case of a six-year-old male who sustained a ventricular septal defect following blunt trauma to the chest. Traumatically acquired VSD is rare in children. The diagnosis is made by characteristic history and physical examination and confirmed by echocardiogram or cardiac catheterization. Treatment is medical until surgical repair can be safely accomplished.

Child↗

Treatment of triple tooth: report of case.

A case of a young girl with a triple primary tooth that retarded normal development of the maxillary left lateral incisor is described. The primary tooth was extracted to encourage normal development of the permanent tooth. Subsequent examination of the extracted triple tooth suggests that it was composed of the primary left lateral incisor fused either to a geminated central incisor or to a fused central incisor and supernumerary tooth.

Child↗

Oral hemorrhage associated with periodontal surgery and hypertensive crisis.

A case of accelerated hypertension associated with severe oral hemorrhage is described. The evidence in this case suggests that a hypertensive crisis may have been caused by a failure to take medication as prescribed, or may have occurred as a sequel to severe postoperative hemorrhage. The reopening of the surgical site was probably caused by masticatory trauma, and the hemorrhage exacerbated by localized fibrinolytic activity.

Blood Pressure↗

Dental caries prevalence in children with a diet free of refined sugar.

A study of the caries and dental hygiene status of 73 children living in the Synanon community revealed a mean DMF-S score at 0.53 for the 5-10 year old group and 3.33 for the 11-17 year old group. In spite of poor oral hygiene, 53 per cent of the children were caries-free and none of the children was missing permanent teeth. The children had consumed a diet free of refined carbohydrates for five years and had received optimal fluoride supplementation since birth or joining Synanon.

Adolescent↗

Practical issues in the care of pediatric trauma patients.

Childhood injuries are a preventable problem that continue to occur with alarming frequency. The pediatrician has a broad role in the prevention and treatment of injuries. When primary prevention fails, trauma care providers must recognize that an injured child is a unique patient who requires special considerations. Use of an organized approach will assure that injuries are not missed. The care of an injured child presents pediatricians with a tremendous responsibility. Injury prevention presents the pediatrician with a formidable challenge.

Adolescent↗

Interpreting the toxicologic significance of alterations in anogenital distance: potential for confounding effects of progeny body weights.

Anogenital distance (AGD) is an endpoint that was recently added to the U.S. EPA testing guidelines for reproductive toxicity studies. This endpoint is sensitive to hormonal effects of test chemicals. It is possible that apparent alterations in AGD might occur after treatment with agents that affect overall pup body size. In such cases, hormonal activity might be associated incorrectly with the test treatment. The analyses in this report evaluated statistical correlations between pup body weight and AGD in control litters. AGDs were measured on postnatal day 1 in 1501 pups derived from 113 untreated female Sprague-Dawley rats in two independent two-generation reproductive toxicity studies. Significant correlations were detected between AGD and body weight and between AGD and the cube root of body weight. In males, AGD increased 0.26 mm for each 1 g increase in body weight. In females, AGD increased 0.13 mm per 1 g increase in body weight. Although there were essentially no differences between the regression models developed to predict AGD in either males or females using body weight as a covariate and those based on the cube root of body weight, such similarities in predictivity might not occur in larger animals with broader weight ranges than those encountered in this analysis. Normalization of AGD by dividing by body weight significantly overcompensated for differences in body size. Normalizing with the cube root of body weight resulted in an AGD/cube root of body weight ratio that was constant across the range of body weights observed in this study. In conclusion, as a preferred method to account for body size effects on AGD, analysis of covariance is recommended. If a normalization is done directly, the ratio of AGD to the cube root of body weight is the more appropriate metric.

Animals↗

Dentofacial trauma in children.

Most of the literature on dental injury pertains to the classification, incidence, prevalence, and treatment of fractured teeth. A major finding here is that the five leading causes of dentofacial injuries, regardless of severity, were falls, being struck by an object, bicycle accidents, assaults, and motor vehicle accidents.

Accidents↗