Biomedical subjects
Publications and source records attributed to J F Johnson.
Two cases of Hirschsprung's disease with psuedotransition zones are presented. The location and appearance of the transition zone, transverse contractions proximal to the radiographic transition zone, and a delayed film aid in distinguishing a false transition zone from a true transition zone.
A four-year-old boy presented with a soft tissue mass containing ringlet calcifications associated with fracture and irregular osteolysis of the underlying public ramus. Although the radiographic appearance suggested malignancy, the evolution of the lesion confirmed that it was post-traumatic.
A case of neonatal hemoperitoneum secondary to umbilical artery catheterization is presented. The only sign of arterial laceration was a rapid accumulation of intraperitoneal fluid following placement of the catheter.
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Illustrated are the principles for isolating proteins from solution by sorption into a polymer gel phase, driven by the addition of a water-soluble polymer to the protein solution. The separation is shown to be analogous to conventional two-phase aqueous extraction. However, the use of a gel phase rather than a solution for absorbing the protein makes separation of the protein from the polymer and the recycling of the gel phase much simpler. The model system used was linear poly(ethylene glycol) (PEG) and dextran gel. Increasing the molecular weight and concentration of the PEG favored sorption by the gel of ovalbumin, bovine serum albumin, cytochrome c, and hemoglobin. The proteins could be quantitatively recovered by immersing the gel in PEG-free solution.
OBJECTIVE: To identify problems with medication knowledge, self-estimated compliance, and recall of medication education in a group of elderly patients. DESIGN: Survey. SETTING: Medicine and geriatric clinics at a county hospital. PATIENTS: Patients greater than or equal to 60 years old and taking at least one prescription medication. MAIN OUTCOME MEASUREMENTS: Medication knowledge, self-estimated compliance, and recall of medication education. RESULTS: The percent of geriatric patients correctly stating 76-100 percent of their medication doses, uses, and frequencies was 30, 64, and 66 percent, respectively. Fifteen patients (34 percent) stated they never missed a medication dose and 27 (61 percent) remembered to take their medications by memory alone. Sixteen and 86 percent, respectively, of the patients from the medicine and geriatric clinics could not recall receiving verbal or written educational material. Only 27 percent of patients recalled having been told about possible adverse reactions. The most frequently cited providers of medication information were physicians. CONCLUSIONS: Specially designed multidisciplinary medication education programs with repeated written and verbal reinforcement for elderly patients may improve patients' knowledge about their medications, recognition and management of adverse reactions, and compliance.