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Biomedical subjects

J F Jabre

Publications and source records attributed to J F Jabre.

25 records · Page 2Linked to original sources

Surface recording of the H-reflex of the flexor carpi radialis.

Although the H-reflex of the triceps surae is used routinely in nerve conduction studies of the lower extremities, doubt still exists concerning the H-reflex in the upper extremities. The H-reflex of the flexor carpi radialis is easily obtainable and can be recorded by a simple nerve conduction technique detailed in this communication.

Adolescent↗

An EMG study of functional cortico-motoneuronal connections in humans.

We set out to decompose the EMG signal into its constituent motor unit action potential components to track motor unit firing rates with a high degree of accuracy and extract their average firing rate. We were able to show that this average firing rate tracks the subject's force trajectory from beginning to end. We propose that this average firing rate is a volitional control signal pointing to the existence of a 'volitional unit'. This volitional unit has to do with the projection of a group of functionally related cortico-motoneurons on a group of spinal motoneurons in the motoneuronal pool of a muscle. Our study of motor unit firing patterns during their steady state showed that spinal motoneurons respond to a descending central input in a Gaussian manner. We have further shown that the central drive itself, as represented by the average firing rate of the active motor units, also displays a Gaussian firing behavior. We have also described the existence of a 'translation factor', highly correlated to the motor unit size, which is unique to each spinal motoneuron and determines the motoneuronal response, and its resulting firing rate, to the descending inputs. As for force generation, we have shown that expressing the twitch force of a motor unit in a dynamic fashion using the 'electrotwitch' concept of firing rate x macro area, approximates motor unit force output better and accounts for firing rate related force changes more effectively than force estimates based on the mechanical twitch.

Adult↗

The use of multiple Tinel's sign in the identification of patients with peripheral neuropathy.

We have found that the presence of a Tinel's sign is often pervasive in subjects with peripheral neuropathy and/or risk factors for developing it. There is a paucity of research dealing with the usefulness of Tinel's sign as it relates to peripheral neuropathy (PN). The following investigation was carried out to determine if multiple Tinel's sign or MTS can be used to identify patients with an underlying PN or with risk factors for developing a PN. A total of 102 subjects were enrolled in the study prospectively. We found MTS to have a sensitivity of 79% with a specificity of 42% in detecting peripheral neuropathy and a sensitivity of 76% with a specificity of 44% in determining the presence of risk factors for developing a peripheral neuropathy. We conclude that MTS can be a fairly sensitive indicator of PN or risk factors.

Adult↗

Distal, "Tinel-like" percussion paresthesiae, with proximal nerve lesions.

Can proximal nerve lesions cause a distal "Tinel-like" sign? We present the case studies of two patients with documented cervical root lesions who exhibited percussion paresthesiae distally in the absence of any clinical or nerve conduction evidence of distal pathology. The possible mechanisms underlying such manifestation, which has been previously reported in the literature, are explored, and a case is made for the phenomenon being related to the "distortion" of a normal sensory signal when it encounters an area of spatial inhomogeneity proximally along the nerve.

Adult↗