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Biomedical subjects

J F Fielding

Publications and source records attributed to J F Fielding.

At least 91 records · Page 5Linked to original sources
PubMed1983

Proctitis.

Explore the source record for details and available documents.

Colitis, Ulcerative↗
PubMed1982

The prevalence and significance of gastritis in patients with lower intestinal irritable bowel (irritable colon) syndrome.

Histological gastritis was present in nearly two-thirds of consecutive patients with lower intestinal irritable bowel (irritable colon) syndrome. The presence of gastritis had no relationship to upper intestinal symptoms; we believe that upper intestinal symptoms in these patients are therefore unlikely to be due to coexistent gastritis. Abnormal pyloroduodenal motility with consequent abnormal bile reflux or clearance may account for gastritis in patients with irritable colon. This study, admittedly uncontrolled, provides further indirect evidence to support the concept of a widespread neuromuscular abnormality throughout the gastrointestinal tract in irritable bowel syndrome patients who have predominantly colonic symptoms.

Adolescent↗
PubMed1982

Domperidone treatment in the irritable bowel syndrome.

Domperidone treatment did not differ significantly from placebo treatment in irritable bowel syndrome patients concurrently put on high fibre diet. No side effects attributable to the drug were encountered. This study further reinforces the necessity to have patients concurrently on a high fibre diet when testing for drug efficiency in the irritable bowel syndrome. Double-blind drug versus placebo studies should be undertaken in the irritable bowel syndrome patients who fail to respond to a high fibre diet. Dopamine receptor sites are unlikely to be primarily involved in the irritable bowel syndrome.

Adolescent↗