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Biomedical subjects

J F Dymling

Publications and source records attributed to J F Dymling.

At least 37 records · Page 2Linked to original sources
PubMed1979

Effect of danazol on thyroid function in women.

A longitudinal study of thyroid function during danazol treatment was performed in 18 women. Serum concentrations of thyroid stimulating hormone (TSH), thyroxine (T4), tri-iodothyronine (T3), free T4-and free T3 index as well as thyroid hormone binding globulin (TBG) were measured before and during 6 months therapy. Thyroxine binding globulin showed a marked decrease to one third of the pretreatment level. All the hormones showed significant alterations within the normal ranges for this group. T3 and T4 decreased slightly and the free T4 and free T3 index showed an increase. TSH decreased from 2.4 +/- 0.6 to 1.7 +/- 0.3 mIU/l. The observed hormonal changes were most likely induced by the decreased TBG concentrations and were probably without pathological significance. However these changes must be kept in mind when thyroid function tests from patients with danazol are evaluated.

Adult↗
PubMed1979

Bilateral renal artery stenosis/occlusion and renovascular hypertension. Correlation of angiographic findings with blood pressure response after surgery.

In a previous study of unilateral renal artery stenosis the angiograms of patients with a favourable blood pressure response after surgery were found to be characterized by a reduction of renal arterial lumen greater than or equal to 90% and/or renal collateral circulation. Ancillary features were post-stenotic dilatation and a reduction of kidney length greater than or equal to 1 cm (Andersson; Andersson, Bergentz, Dymling, Ericsson, Hansson & Hökfelt). This report deals with 32 patients with bilateral renal artery stenosis who were followed 6--54 months after operation. The preoperative angiograms were analysed retrospectively without knowledge of the blood pressure response. In patients with bilateral fibromuscular dysplasia a good correlation was found between the above-mentioned criteria and a favourable blood pressure respone. In patients with bilateral arteriosclerotic stenosis no correlation was found. It was concluded that renal angiography constitutes a valuable predictive test in bilateral non-arteriosclerotic stenosis. In the presence of bilateral arteriosclerotic stenosis the selection of patients for surgery should be based on other parameters such as kidney function, age and general vascular status of the patient.

Adult↗
PubMed1978

Progression of a structural scoliosis during treatment with growth hormone. A case report.

A diagnosis of panhypopituitarism was made in an infantile male at the age of 22. Skeletal age was estimated to be 14 years. Thyroxin, corticosteroid and later testosterone was administered. Growth hormone was given initially over a period of ten weeks and later for two and a half years. The standing height increased from 143 to 158.5 cm. During periods of growth induced by growth hormone a progression of a thoracic scoliosis from 15 degrees to 62 degrees was observed. In this case growth hormone or the associated substances seem to be the more probable cause of the progression of scoliosis than growth rate per se.

Adrenal Cortex Hormones↗
PubMed1976

Whisky: a new provacative test for calcitonin secretion.

Oral whisky is a potent stimulus of calcitonin secretion. Peak increments of immunoreactive calcitonin are observed within 15 min after the ingestion of 50 ml of whisky; the magnitude of the response is similar to that observed during a four-hour calcium infusion. This procedure has several advantages over standard methods of stimulating calcitonin release in patients at risk of developing medullary carcinoma of the thyroid, and this is shown by a study in a large family with familial chromaffinomatosis.

Adolescent↗