Biomedical subjects
Publications and source records attributed to J F Cullen.
A patient presented with headache, soreness over her scalp and general malaise. She was treated for hypertension, but later went blind in one eye. Following referral to the Eye Department, she was treated successfully for six episodes of blindness in her second eye. The case highlights the ways in which temporal arteritis may present. Prompt treatment will save vision, but a missed diagnosis may result in blindness.
A consecutive series of 116 Severin lens implantations with a mean follow-up time of 9 months was reported 2 years ago. In view of the excellent early outcome the series was continued and the results of the initial series is further reviewed at a mean follow-up time of 28 months. The entire series of 305 Severin lens implantations with a mean follow-up time of 21 months is reported. The early results are compared with the longer term results. Intraocular lens implantation in the United Kingdom is equally divided between extracapsular extractions with a posterior chamber lens and intracapsular extractions with an iris fixated lens, anterior chamber lenses taking third place. While the advantages of the extracapsular technique are undisputed, until YAG Lasers are more widely available for dealing with thickened posterior capsules, an intracapsular technique with an iris fixated lens may still have a place.
Experience with 116 consecutive posterior chamber Severin intraocular lenses following intracapsular extraction is described. The low incidence of complications in this series of selected patients and the good visual results are emphasized.
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Three cases of metastatic carcinoma to the pituitary gland presenting with local compression, causing field defects and nerve palsies are reported. The literature on secondary tumours in the pituitary is reviewed and the differentiation between benign and metastatic lesions is discussed. The importance of making the diagnosis preoperatively is emphasized.
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A total of 136 patients with histologically proven temporal arteritis were seen in the Lothian Region of Scotland in the 14-year period, 1964-77. This study is a review of these cases with particular reference to incidence, age, sex, seasonal occurrence, along with clinical features, general and visual prognosis. It also comments on treatment, the adverse effects thereof, and the differential diagnosis. A seasonal effect significant at the 1 per cent level was established with a peak occurrence in January.
Of the 82 patients who presented to our clinic with unilateral blindness secondary to diabetic retinopathy, 76% had PDR in the blind eye, 4% had non-proliferative retinopathy, and 20% had macular exudates. The second eye, in most instances, had or developed the same pathology as the first eye. Visual prognosis was poor for the 59 patients who had PDR in the second eye; 24 became blind at an average of 15-7 months after presentation. Those patients who were treated seemed to fare better than those not treated. Only three of the fourteen patients who had pituitary ablations became blind, but the average age of this group was, of course, significantly lower than that of the others. Nine of the 22 patients who received photocoagulation became blind in the second eye. Twelve of the 24 patients who received no treatment became blind in the second eye. Visual prognosis for patients with non-proliferative retinopathy was much better; ten patients maintained useful vision for an average of 4 years follow-up. Of the twelve patients with macular exudates in the second eye, three became blind at an average of 34 months after presentation.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.