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Biomedical subjects

J F Boyd

Publications and source records attributed to J F Boyd.

At least 55 records · Page 3Linked to original sources
PubMed1973

An outbreak of infantile gastroenteritis due to E. coli 0142.

Twelve cases of gastroenteritis caused by Escherichia coli 0142K86H6 are described. Ten of these cases were clearly involved in an outbreak of cross infection. The other two cases yielded interesting information on infection with E. coli. 0142. Five cases, two being fatal, required repeated intravenous infusion, and one further infant required parenteral replacement therapy on a single occasion only. Cross infection occurred at the primary site-a ward partitioned into cubicles-despite full barrier nursing techniques. Infection spread also to two other wards, and resulted from transfer of latently infected cases. Illness in several infants was protracted and debilitating because of the relapsing nature of the infection. The pathology of the two fatalities is reported briefly.

Cross Infection↗
PubMed1969

Disseminated fibrin thromboembolism among neonates dying more than 48 hours after birth.

Of 119 neonates dying after 48 hours of life, 19 (16%) showed disseminated fibrin thromboembolism, a histological condition that is very similar to one form of maternal hypofibrinogenaemia. The incidence is nearly five times that among stillbirths and neonates dying within 48 hours of birth. Most of the mothers had a normal pregnancy, labour, and puerperium. One twin may show the condition while the other survives. It is suggested that the affected infants have either no fibrinolytic mechanism, a defective one, or one which for some unaccountable reason was not brought into action. The antecedent plasma fibrinogen level is likely to have been high in some cases, but a fatal outcome can ensue with normal or low levels. The process was considered to be totally responsible for death in six cases (5%) of the series. Renal tubular hyaline droplets apparently rich in haemoglobin were only encountered in one infant (no. 4) who died from massive bilateral adrenal haemorrhage. In the later part of the neonatal period, the process is liable to be indistinguishable clinically from secondary thrombotic processes, which occurred with almost the same incidence in the present series (14(12%) of 119 cases).

Adrenal Glands↗